FJ9 | CAS# 873841-43-1 | FZD7 Inhibitor

MedKoo Cat#: 564562 | Name: FJ9

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FJ9 is a FZD7 inhibitor which disrupts protein-protein interaction between Frz7 and the PDZ domain of DVL, and induces apoptosis in melanoma cell line and non-small cell lung cancer cell line.

Chemical Structure

FJ9

CAS# 873841-43-1

Theoretical Analysis

MedKoo Cat#: 564562

Name: FJ9

CAS#: 873841-43-1

Chemical Formula: C23H27NO3

Exact Mass: 365.1991

Molecular Weight: 365.47

Elemental Analysis: C, 75.59; H, 7.45; N, 3.83; O, 13.13

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

FJ-9; FJ 9; FJ9

IUPAC/Chemical Name

2-(1-Hydroxypentyl)-6-methyl-3-phenethyl-1H-indole-5-carboxylic acid

InChi Key

CTHUKURTASAUTM-UHFFFAOYSA-N

InChi Code

InChI=1S/C23H27NO3/c1-3-4-10-21(25)22-17(12-11-16-8-6-5-7-9-16)19-14-18(23(26)27)15(2)13-20(19)24-22/h5-9,13-14,21,24-25H,3-4,10-12H2,1-2H3,(H,26,27)

SMILES Code

O=C(C1=CC2=C(NC(C(O)CCCC)=C2CCC3=CC=CC=C3)C=C1C)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 365.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kweon SM, Chi F, Higashiyama R, Lai K, Tsukamoto H. Wnt Pathway Stabilizes MeCP2 Protein to Repress PPAR-γ in Activation of Hepatic Stellate Cells. PLoS One. 2016 May 23;11(5):e0156111. doi: 10.1371/journal.pone.0156111. eCollection 2016. PubMed PMID: 27214381; PubMed Central PMCID: PMC4877088.