MedKoo Cat#: 555378 | Name: GSK1940029
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GSK1940029, also known as SCD Inhibitor 1, is a SCD Inhibitor. GSK1940029 is a potential topical treatment of acne,

Chemical Structure

GSK1940029
GSK1940029
CAS#1150701-66-8

Theoretical Analysis

MedKoo Cat#: 555378

Name: GSK1940029

CAS#: 1150701-66-8

Chemical Formula: C18H16Cl2N4O2

Exact Mass: 390.0650

Molecular Weight: 391.25

Elemental Analysis: C, 55.26; H, 4.12; Cl, 18.12; N, 14.32; O, 8.18

Price and Availability

Size Price Availability Quantity
5mg USD 80.00 Ready to ship
10mg USD 150.00 Ready to ship
25mg USD 250.00 Ready to ship
50mg USD 450.00 Ready to ship
100mg USD 850.00 Ready to ship
200mg USD 1,250.00 Ready to ship
500mg USD 2,150.00 Ready to ship
1g USD 3,250.00 Ready to ship
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Related CAS #
No Data
Synonym
GSK1940029; GSK-1940029; GSK 1940029; SCD Inhibitor 1;
IUPAC/Chemical Name
1-[(3,4-dichlorophenyl)methyl]-N-[4-(hydroxymethyl)phenyl]-5-methyltriazole-4-carboxamide
InChi Key
QQRGSFYTPBYCFD-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H16Cl2N4O2/c1-11-17(18(26)21-14-5-2-12(10-25)3-6-14)22-23-24(11)9-13-4-7-15(19)16(20)8-13/h2-8,25H,9-10H2,1H3,(H,21,26)
SMILES Code
O=C(C1=C(C)N(CC2=CC=C(Cl)C(Cl)=C2)N=N1)NC3=CC=C(CO)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 391.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Brigandi RA, Zhu J, Murnane AA, Reedy BA, Shakib S. A Phase 1 Randomized, Placebo-Controlled Trial With a Topical Inhibitor of Stearoyl-Coenzyme A Desaturase 1 Under Occluded and Nonoccluded Conditions. Clin Pharmacol Drug Dev. 2019 Apr;8(3):270-280. doi: 10.1002/cpdd.644. Epub 2019 Jan 16. PubMed PMID: 30650256; PubMed Central PMCID: PMC6590436.