MedKoo Cat#: 573165 | Name: Warfarin potassium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Warfarin potassium, also known as Coumadin, is an anticoagulant. It is used to treat blood clots such as deep vein thrombosis and pulmonary embolism and to prevent stroke in people who have atrial fibrillation, valvular heart disease or artificial heart valves.

Chemical Structure

Warfarin potassium
Warfarin potassium
CAS#2610-86-8 (potassium)

Theoretical Analysis

MedKoo Cat#: 573165

Name: Warfarin potassium

CAS#: 2610-86-8 (potassium)

Chemical Formula: C19H15KO4

Exact Mass: 346.0607

Molecular Weight: 346.42

Elemental Analysis: C, 65.88; H, 4.36; K, 11.29; O, 18.47

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Antrombin K, Coumadin, Warfarin K, Warfarin potassium
IUPAC/Chemical Name
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin potassium salt
InChi Key
WSHYKIAQCMIPTB-UHFFFAOYSA-M
InChi Code
1S/C19H16O4.K/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22;/h2-10,15,21H,11H2,1H3;/q;+1/p-1
SMILES Code
CC(=O)CC(c1ccccc1)c2c(c3ccccc3oc2=O)[O-].[K+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 346.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jeraj L, Jezovnik MK, Poredos P. Rivaroxaban versus warfarin in the prevention of post-thrombotic syndrome. Thromb Res. 2017 Sep;157:46-48. doi: 10.1016/j.thromres.2017.05.029. Epub 2017 May 29. PubMed PMID: 28692839. 2: Sarratt SC, Nesbit R, Moye R. Safety Outcomes of Apixaban Compared With Warfarin in Patients With End-Stage Renal Disease. Ann Pharmacother. 2017 Jun;51(6):445-450. doi: 10.1177/1060028017694654. Epub 2017 Feb 1. PubMed PMID: 28478715. 3: Ruff CT, Giugliano RP, Braunwald E, Hoffman EB, Deenadayalu N, Ezekowitz MD, Camm AJ, Weitz JI, Lewis BS, Parkhomenko A, Yamashita T, Antman EM. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet. 2014 Mar 15;383(9921):955-62. doi: 10.1016/S0140-6736(13)62343-0. Epub 2013 Dec 4. PubMed PMID: 24315724.