MedKoo Cat#: 573149 | Name: Thonzylamine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thonzylamine hydrochloride is an antihistamine and anticholinergic used as an antipruritic.

Chemical Structure

Thonzylamine hydrochloride
Thonzylamine hydrochloride
CAS# 63-56-9 (HCl)

Theoretical Analysis

MedKoo Cat#: 573149

Name: Thonzylamine hydrochloride

CAS#: 63-56-9 (HCl)

Chemical Formula: C16H23ClN4O

Exact Mass: 322.1560

Molecular Weight: 322.84

Elemental Analysis: C, 59.53; H, 7.18; Cl, 10.98; N, 17.35; O, 4.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Thonzylamine hydrochloride, Anahist, Neohetramine hydrochloride, Novohetramin, Resistab, Thonzylamine HCl
IUPAC/Chemical Name
2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyrimidine hydrochloride
InChi Key
HRYJPHOTGFERGT-UHFFFAOYSA-N
InChi Code
1S/C16H22N4O.ClH/c1-19(2)11-12-20(16-17-9-4-10-18-16)13-14-5-7-15(21-3)8-6-14;/h4-10H,11-13H2,1-3H3;1H
SMILES Code
N(c1ncccn1)(Cc1ccc(OC)cc1)CCN(C)C.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 322.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sabry SM, Abdel-Hay MH, Barary MH, Belal TS. Sensitive spectrofluorimetric and spectrophotometric methods for the determination of thonzylamine hydrochloride in pharmaceutical preparations based on coupling with dimethylbarbituric acid in presence of dicyclohexylcarbodiimide. J Pharm Biomed Anal. 2000 Mar;22(2):257-64. PubMed PMID: 10719908. 2: DREYER NB, SLAVIN WJ. Effect of an antihistaminic drug (thonzylamine) on uterine contractility. J Am Med Womens Assoc. 1954 Feb;9(2):35-8. PubMed PMID: 13142908. 3: DUCA CJ, ROTHLAUF MV, SCUDI JV. Further studies on thonzylamine in treatment of experimental tuberculosis. Proc Soc Exp Biol Med. 1951 Aug;77(4):641-3. PubMed PMID: 14891823.