NSC781406 is a highly potent PI3K/mTOR dual inhibitor, exhibiting potent tumor growth inhibition in the hepatocellular carcinoma BEL-7404 xenograft model.
MedKoo Cat#: 564415
Name: NSC781406
CAS#: 1676893-24-5
Chemical Formula: C29H27F2N5O5S2
Exact Mass: 627.1422
Molecular Weight: 627.68
Elemental Analysis: C, 55.49; H, 4.34; F, 6.05; N, 11.16; O, 12.74; S, 10.22
Solvent | mg/mL | mM | |
---|---|---|---|
Solubility | |||
DMF | 10.0 | 15.93 | |
DMSO | 85.0 | 135.42 | |
DMSO:PBS (pH 7.2) (1:4) | 0.2 | 0.32 |
The following data is based on the product molecular weight 627.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |