MedKoo Cat#: 564405 | Name: AZ617 Sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AZ617 Sodium is a water soluble, potent TLR4 agonist.

Chemical Structure

AZ617 Sodium
AZ617 Sodium
CAS#AZ617 Sodium

Theoretical Analysis

MedKoo Cat#: 564405

Name: AZ617 Sodium

CAS#: AZ617 Sodium

Chemical Formula: C40H37N4NaO4

Exact Mass: 0.0000

Molecular Weight: 660.75

Elemental Analysis: C, 72.71; H, 5.64; N, 8.48; Na, 3.48; O, 9.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
AZ-617 Sodium; AZ 617 Sodium; AZ617 Sodium
IUPAC/Chemical Name
Sodium (4-{cyclopentylcarbamoyl-[(1,5-diphenyl-1H-pyrazole-3-carbonyl)-indan-5-yl-amino]-methyl}-phenyl)-acetate
InChi Key
MDVBAWHHPYEIOT-UHFFFAOYSA-M
InChi Code
InChI=1S/C40H38N4O4.Na/c45-37(46)24-27-18-20-30(21-19-27)38(39(47)41-32-14-7-8-15-32)43(34-23-22-28-12-9-13-31(28)25-34)40(48)35-26-36(29-10-3-1-4-11-29)44(42-35)33-16-5-2-6-17-33;/h1-6,10-11,16-23,25-26,32,38H,7-9,12-15,24H2,(H,41,47)(H,45,46);/q;+1/p-1
SMILES Code
O=C([O-])CC1=CC=C(C(C(NC2CCCC2)=O)N(C(C3=NN(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3)=O)C6=CC7=C(CCC7)C=C6)C=C1.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 660.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Twomey R, Graham S, Spina JS, Wu X, Dubé PE, Ferrebee C, Housley W. Utilizing a human TLR selective ligand in a humanized immune system mouse model to investigate human TLR4 signaling. J Biol Methods. 2023 Nov 20;10:jbm-10-e99010008. doi: 10.14440/jbm.2023.408. PMID: 38046987; PMCID: PMC10691501.