ZX-J-19J | CAS#1352576-02-3 | CyPJ PPIase Inhibitor

MedKoo Cat#: 564057 | Name: ZX-J-19J

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZX-J-19J is an inhibitor of Cyclophilin J (CyPJ) PPIase. ZX-J-19J demonstrates remarkable inhibition of tumor cell growth, comparable to CsA but much stronger than 5-fluorouracil.

Chemical Structure

ZX-J-19J

CAS#1352576-02-3

Theoretical Analysis

MedKoo Cat#: 564057

Name: ZX-J-19J

CAS#: 1352576-02-3

Chemical Formula: C28H29N3O

Exact Mass: 423.2311

Molecular Weight: 423.56

Elemental Analysis: C, 79.40; H, 6.90; N, 9.92; O, 3.78

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

ZX-J-19J; ZXJ19J; ZX J 19J; ZXJ-19J; ZXJ 19J

IUPAC/Chemical Name

N-(2,3-diphenylquinoxalin-6-yl)octanamide

InChi Key

MNQBMADDNFMNDR-UHFFFAOYSA-N

InChi Code

InChI=1S/C28H29N3O/c1-2-3-4-5-12-17-26(32)29-23-18-19-24-25(20-23)31-28(22-15-10-7-11-16-22)27(30-24)21-13-8-6-9-14-21/h6-11,13-16,18-20H,2-5,12,17H2,1H3,(H,29,32)

SMILES Code

CCCCCCCC(NC1=CC=C2N=C(C3=CC=CC=C3)C(C4=CC=CC=C4)=NC2=C1)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 423.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Zhao X, Xia C, Wang X, Wang H, Xin M, Yu L, Liang Y. Cyclophilin J PPIase Inhibitors Derived from 2,3-Quinoxaline-6 Amine Exhibit Antitumor Activity. Front Pharmacol. 2018 Feb 21;9:126. doi: 10.3389/fphar.2018.00126. eCollection 2018. PubMed PMID: 29520233; PubMed Central PMCID: PMC5826973.