T1742, also known as 4E 1RCat, is an autophagy Inhibitor by disrupting the Protein−Protein Interactions Involving Autophagy-Related 5. T1742 blocked the ATG5−ATG16L1 and ATG5−TECAIR interactions in the in vitro binding assay (IC50 = 1−2 μM) and also exhibited autophagy inhibition in cellular assays.
MedKoo Cat#: 122724
Name: T1742
CAS#: 1815600-11-3
Chemical Formula: C28H18N2O6
Exact Mass: 478.1200
Molecular Weight: 478.46
Elemental Analysis: C, 70.29; H, 3.79; N, 5.86; O, 20.06
The following data is based on the product molecular weight 478.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
-Polydatin1853.jpg "(E/Z)-Polydatin")
