Synonym
Perfluoropentane; Dodecafluoropentane; DDFP; NVX108; NVX 108; NVX-108
IUPAC/Chemical Name
Perfluoropentane; Dodecafluoropentane
InChi Key
NJCBUSHGCBERSK-UHFFFAOYSA-N
InChi Code
InChI=1S/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17
SMILES Code
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
288.04
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Mullah SH, Saha BK, Abutarboush R, Walker PB, Haque A, Arnaud FG, Hazzard B, Auker CR, McCarron RM, Scultetus AH, Moon-Massat P. Perfluorocarbon NVX-108 increased cerebral oxygen tension after traumatic brain injury in rats. Brain Res. 2016 Mar 1;1634:132-139. doi: 10.1016/j.brainres.2016.01.012. Epub 2016 Jan 12. PubMed PMID: 26794250.
2: Moon-Massat PF, Abutarboush R, Pappas G, Haque A, Aligbe C, Arnaud F, Auker C, McCarron R, Scultetus A. Effects of perfluorocarbon dodecafluoropentane (NVX-108) on cerebral microvasculature in the healthy rat. Curr Drug Discov Technol. 2014;11(3):220-6. PubMed PMID: 25007887.
