MedKoo Cat#: 581379 | Name: Tridecactide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tridecactide is a 13-amino acid peptide derived from proteolytic cleavage of Adrenocorticotropic hormone at the N-terminal of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of melanin in Melanocytes in mammals and Melanophores in lower vertebrates.

Chemical Structure

Tridecactide
Tridecactide
CAS#22006-64-0

Theoretical Analysis

MedKoo Cat#: 581379

Name: Tridecactide

CAS#: 22006-64-0

Chemical Formula: C75H106N20O19S

Exact Mass: 1622.7664

Molecular Weight: 1623.85

Elemental Analysis: C, 55.47; H, 6.58; N, 17.25; O, 18.72; S, 1.97

Price and Availability

Size Price Availability Quantity
1mg USD 500.00 2 Weeks
5mg USD 1,300.00 2 Weeks
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Related CAS #
Synonym
Tridecactide; ACTH(1-13); alpha1-13-Corticotropin; DE-alpha-Msh;
IUPAC/Chemical Name
(4S,7S,10S,13S,16S,22S)-7-((1H-imidazol-5-yl)methyl)-16-((1H-indol-3-yl)methyl)-26-amino-4-((S)-2-((S)-2-((S)-2-((S)-2-amino-3-hydroxypropanamido)-3-(4-hydroxyphenyl)propanamido)-3-hydroxypropanamido)-4-(methylthio)butanamido)-10-benzyl-22-((S)-2-(((S)-1-carboxy-2-methylpropyl)carbamoyl)pyrrolidine-1-carbonyl)-13-(3-guanidinopropyl)-5,8,11,14,17,20-hexaoxo-6,9,12,15,18,21-hexaazahexacosanoic acid
InChi Key
VGBVAARMQYYITG-DESRROFGSA-N
InChi Code
1S/C75H106N20O19S/c1-41(2)62(74(113)114)94-72(111)59-19-12-29-95(59)73(112)53(17-9-10-27-76)85-60(99)37-83-64(103)56(33-44-35-82-49-16-8-7-15-47(44)49)91-65(104)50(18-11-28-81-75(78)79)86-68(107)55(31-42-13-5-4-6-14-42)90-70(109)57(34-45-36-80-40-84-45)92-66(105)51(24-25-61(100)101)87-67(106)52(26-30-115-3)88-71(110)58(39-97)93-69(108)54(89-63(102)48(77)38-96)32-43-20-22-46(98)23-21-43/h4-8,13-16,20-23,35-36,40-41,48,50-59,62,82,96-98H,9-12,17-19,24-34,37-39,76-77H2,1-3H3,(H,80,84)(H,83,103)(H,85,99)(H,86,107)(H,87,106)(H,88,110)(H,89,102)(H,90,109)(H,91,104)(H,92,105)(H,93,108)(H,94,111)(H,100,101)(H,113,114)(H4,78,79,81)/t48-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1
SMILES Code
c1(ccc(cc1)O)C[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N[C@H](C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(O)=O)CCCCN)=O)=O)=O)Cc1ccccc1)=O)Cc1[nH]cnc1)=O)CCC(O)=O)=O)CCSC)=O)CO)=O)NC([C@@H](N)CO)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,623.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Omerovic N, Bego T, Prnjavorac B, Smajic NZ, Becic F, Corovic H, Skrbo S. Evaluation of the Effectiveness of Coronavirus Disease (COVID-19) Therapeutic Protocols Using Inflammatory Markers. Acta Inform Med. 2023;31(4):244-248. doi: 10.5455/aim.2023.31.244-248. PMID: 38379683; PMCID: PMC10875952.