Synonym
PPARalpha/gamma agonist N15; MDK80908; MDK-80908; MDK8 0908;
IUPAC/Chemical Name
(Z)-N-(Octadec-9-en-1-yl)propane-2-sulfonamide; Propane-2-sulfonic acid octadec-9-enyl-amide
InChi Key
JLXMADLOPUUMAV-VAWYXSNFSA-N
InChi Code
InChI=1S/C21H43NO2S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-25(23,24)21(2)3/h11-12,21-22H,4-10,13-20H2,1-3H3/b12-11+
SMILES Code
CC(S(=O)(NCCCCCCCC/C=C/CCCCCCCC)=O)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
373.64
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Ren T, Yang WS, Lin Y, Liu JF, Li Y, Yang LC, Zeng KY, Peng L, Liu YJ, Ye ZH, Luo XM, Ke YJ, Diao Y, Jin X. A novel PPARα/γ agonist, propane-2-sulfonic acid octadec-9-enyl-amide, ameliorates insulin resistance and gluconeogenesis in vivo and vitro. Eur J Pharmacol. 2018 May 5;826:1-8. doi: 10.1016/j.ejphar.2018.02.029. Epub 2018 Feb 22. PubMed PMID: 29476879.
2: Li Y, Xu L, Zeng K, Xu Z, Suo D, Peng L, Ren T, Sun Z, Yang W, Jin X, Yang L. Propane-2-sulfonic acid octadec-9-enyl-amide, a novel PPARα/γ dual agonist, protects against ischemia-induced brain damage in mice by inhibiting inflammatory responses. Brain Behav Immun. 2017 Nov;66:289-301. doi: 10.1016/j.bbi.2017.07.015. Epub 2017 Jul 21. PubMed PMID: 28736035.