MedKoo Cat#: 563990 | Name: MDK80908

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MDK80908, also known as PPARalpha/gamma agonist N15, is a dual PPARα/γ agonist, ameliorating insulin resistance and gluconeogenesis in vivo and vitro. MDK80908 has CAS#1821380-90-8.

Chemical Structure

MDK80908
MDK80908
CAS#1821380-90-8 (Z-isomer)

Theoretical Analysis

MedKoo Cat#: 563990

Name: MDK80908

CAS#: 1821380-90-8 (Z-isomer)

Chemical Formula: C21H43NO2S

Exact Mass: 373.3015

Molecular Weight: 373.64

Elemental Analysis: C, 67.51; H, 11.60; N, 3.75; O, 8.56; S, 8.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
1821380-90-8 (Z-isomer) 2180925-86-2 (E-isomer)
Synonym
PPARalpha/gamma agonist N15; MDK80908; MDK-80908; MDK8 0908;
IUPAC/Chemical Name
(Z)-N-(Octadec-9-en-1-yl)propane-2-sulfonamide; Propane-2-sulfonic acid octadec-9-enyl-amide
InChi Key
JLXMADLOPUUMAV-VAWYXSNFSA-N
InChi Code
InChI=1S/C21H43NO2S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-25(23,24)21(2)3/h11-12,21-22H,4-10,13-20H2,1-3H3/b12-11+
SMILES Code
CC(S(=O)(NCCCCCCCC/C=C/CCCCCCCC)=O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 373.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ren T, Yang WS, Lin Y, Liu JF, Li Y, Yang LC, Zeng KY, Peng L, Liu YJ, Ye ZH, Luo XM, Ke YJ, Diao Y, Jin X. A novel PPARα/γ agonist, propane-2-sulfonic acid octadec-9-enyl-amide, ameliorates insulin resistance and gluconeogenesis in vivo and vitro. Eur J Pharmacol. 2018 May 5;826:1-8. doi: 10.1016/j.ejphar.2018.02.029. Epub 2018 Feb 22. PubMed PMID: 29476879. 2: Li Y, Xu L, Zeng K, Xu Z, Suo D, Peng L, Ren T, Sun Z, Yang W, Jin X, Yang L. Propane-2-sulfonic acid octadec-9-enyl-amide, a novel PPARα/γ dual agonist, protects against ischemia-induced brain damage in mice by inhibiting inflammatory responses. Brain Behav Immun. 2017 Nov;66:289-301. doi: 10.1016/j.bbi.2017.07.015. Epub 2017 Jul 21. PubMed PMID: 28736035.