Synonym
Droprenilamine; Valcor.
IUPAC/Chemical Name
Benzenepropanamine, N-(2-cyclohexyl-1-methylethyl)-gamma-phenyl-, (+-)-
InChi Key
HTAFVGKAHGNWQO-HXUWFJFHSA-N
InChi Code
InChI=1S/C24H33N/c1-20(19-21-11-5-2-6-12-21)25-18-17-24(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h3-4,7-10,13-16,20-21,24-25H,2,5-6,11-12,17-19H2,1H3/t20-/m1/s1
SMILES Code
C1CCCC(C1)C[C@@H](C)NCCC(c1ccccc1)c1ccccc1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
335.54
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Nakanishi H, Matsuoka I, Ono T, Yoshida H, Uchibori T, Kogi K. Effect of a prenylamine analog (MG8926) on spontaneous action potentials in isolated rabbit sinoatrial node. Fukushima J Med Sci. 1996 Dec;42(1-2):1-10. PubMed PMID: 9127964.
2: Baratta L, Mastrocola C, Lanciotti G, Petrosillo N, Tubani L, Iannetti A, Avella A. [Comparison of 2 groups of patients with ischemic cardiopathy treated with droprenylamine and prenylamine]. Minerva Cardioangiol. 1982 Jun;30(6):299-302. Italian. PubMed PMID: 7133418.
3: Rengo F, Trimarco B, Volpe M, Ricciadelli B, Morrone G, De Simone A, Condorelli M. [Clinical evaluation of a new antianginal drug: droprenylamine]. G Ital Cardiol. 1980;10(4):473-5. Italian. PubMed PMID: 7002693.
4: Baratta L, Mastrocola C, Petrosillo N, Guerrieri P, Leone G, Lanciotti G. [Clinical and electrocardiographic evaluation of the effectiveness of droprenylamine in patients with ischemic cardiopathy]. Minerva Cardioangiol. 1979 Nov;27(11):709-18. Italian. PubMed PMID: 545178.