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MedKoo Cat#: 341358 | Name: Penicillin V potassium
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Penicillin V potassium is a broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.

Chemical Structure

Penicillin V potassium
Penicillin V potassium
CAS#132-98-9

Theoretical Analysis

MedKoo Cat#: 341358

Name: Penicillin V potassium

CAS#: 132-98-9

Chemical Formula: C16H17KN2O5S

Exact Mass: 388.0495

Molecular Weight: 388.48

Elemental Analysis: C, 49.47; H, 4.41; K, 10.06; N, 7.21; O, 20.59; S, 8.25

Price and Availability

Size Price Availability Quantity
10g USD 195.00
20g USD 350.00
50g USD 650.00
100g USD 950.00
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Related CAS #
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Synonym
Penicillin V potassium; Penicillin VK; HSDB 6315; CCRIS 750; CCRIS-750; CCRIS750.
IUPAC/Chemical Name
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, monopotassium salt, (2S,5R,6R)-
InChi Key
HCTVWSOKIJULET-LQDWTQKMSA-M
InChi Code
InChI=1S/C16H18N2O5S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)24-16)17-10(19)8-23-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
SMILES Code
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(COC3=CC=CC=C3)=O)N1C2=O)[O-].[K+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 388.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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[Erysipelas]. MMW Fortschr Med. 2018 May;160(10):37-40. doi: 10.1007/s15006-018-0580-3. Review. German. PubMed PMID: 29855904. 6: O'Flaherty S, Briner Crawley A, Theriot CM, Barrangou R. The Lactobacillus Bile Salt Hydrolase Repertoire Reveals Niche-Specific Adaptation. mSphere. 2018 May 30;3(3). pii: e00140-18. doi: 10.1128/mSphere.00140-18. Print 2018 Jun 27. PubMed PMID: 29848760; PubMed Central PMCID: PMC5976879. 7: Westensee DK, Rumbold K, Harding KG, Sheridan CM, van Dyk LD, Simate GS, Postma F. The availability of second generation feedstocks for the treatment of acid mine drainage and to improve South Africa's bio-based economy. Sci Total Environ. 2018 Oct 1;637-638:132-136. doi: 10.1016/j.scitotenv.2018.04.410. Epub 2018 May 8. PubMed PMID: 29751295. 8: Bergene EH, Nordeng H, Rø TB, Steinsbekk A. Requests for new oral antibiotic prescriptions in children within 2 days: a Norwegian population-based study. Fam Pract. 2018 May 9. doi: 10.1093/fampra/cmy033. [Epub ahead of print] PubMed PMID: 29746693. 9: Dabija-Wolter G, Al-Zubaydi SS, Mohammed MMA, Bakken V, Bolstad AI. The effect of metronidazole plus amoxicillin or metronidazole plus penicillin V on periodontal pathogens in an in vitro biofilm model. Clin Exp Dent Res. 2018 Jan 2;4(1):6-12. doi: 10.1002/cre2.96. eCollection 2018 Feb. PubMed PMID: 29744209; PubMed Central PMCID: PMC5813892. 10: Asgary S, Roghanizadeh L. Rapid Bone Healing after Intentional Replantation of a Molar with Apical Actinomycosis. Iran Endod J. 2018 Winter;13(1):135-138. doi: 10.22037/iej.v13i1.19369. PubMed PMID: 29692850; PubMed Central PMCID: PMC5800456. 11: Hertz FB, Jensen A, Knudsen JD, Arpi M, Andersson C, Gislason GH, Køber L, Torp-Pedersen C, Lippert F, Weeke PE. Does macrolide use confer risk of out-of-hospital cardiac arrest compared with penicillin V? A Danish national case-crossover and case-time-control study. BMJ Open. 2018 Feb 23;8(2):e019997. doi: 10.1136/bmjopen-2017-019997. PubMed PMID: 29476030; PubMed Central PMCID: PMC5855353. 12: Chand D, Panigrahi P, Varshney N, Ramasamy S, Suresh CG. Structure and function of a highly active Bile Salt Hydrolase (BSH) from Enterococcus faecalis and post-translational processing of BSH enzymes. Biochim Biophys Acta. 2018 Apr;1866(4):507-518. doi: 10.1016/j.bbapap.2018.01.003. Epub 2018 Jan 8. PubMed PMID: 29325872. 13: Dumpis U, Hahlin A, Varvuolyte S, Stenmark S, Veide S, Valinteliene R, Jurkeviciene A, Struwe J. Antibiotic prescription and clinical management of common infections among general practitioners in Latvia, Lithuania, and Sweden: a pilot survey with a simple protocol. Eur J Clin Microbiol Infect Dis. 2018 Feb;37(2):355-361. doi: 10.1007/s10096-017-3141-2. Epub 2017 Dec 7. PubMed PMID: 29218467; PubMed Central PMCID: PMC5780528. 14: Inghammar M, Nibell O, Pasternak B, Melbye M, Svanström H, Hviid A. Long-Term Risk of Cardiovascular Death With Use of Clarithromycin and Roxithromycin: A Nationwide Cohort Study. Am J Epidemiol. 2018 Apr 1;187(4):777-785. doi: 10.1093/aje/kwx359. PubMed PMID: 29155931. 15: Tse R, Garland J, Ahn Y. Decline in 2 Serial Postmortem Tryptase Measurements Beyond 72 Hours After Death in an Antibiotic-Related Anaphylactic Death. Am J Forensic Med Pathol. 2018 Mar;39(1):14-17. doi: 10.1097/PAF.0000000000000363. PubMed PMID: 29135492. 16: Delungahawatta T, Amin JY, Stanisz AM, Bienenstock J, Forsythe P, Kunze WA. Antibiotic Driven Changes in Gut Motility Suggest Direct Modulation of Enteric Nervous System. Front Neurosci. 2017 Oct 20;11:588. doi: 10.3389/fnins.2017.00588. eCollection 2017. PubMed PMID: 29104530; PubMed Central PMCID: PMC5655012. 17: Basetti S, Hodgson J, Rawson TM, Majeed A. Scarlet fever: a guide for general practitioners. London J Prim Care (Abingdon). 2017 Aug 11;9(5):77-79. doi: 10.1080/17571472.2017.1365677. eCollection 2017 Sep. Review. PubMed PMID: 29081840; PubMed Central PMCID: PMC5649319. 18: Llor C, Pérez A, Carandell E, García-Sangenís A, Rezola J, Llorente M, Gestoso S, Bobé F, Román-Rodríguez M, Cots JM, Hernández S, Cortés J, Miravitlles M, Morros R. Efficacy of high doses of penicillin versus amoxicillin in the treatment of uncomplicated community acquired pneumonia in adults. A non-inferiority controlled clinical trial. Aten Primaria. 2017 Oct 20. pii: S0212-6567(17)30234-2. doi: 10.1016/j.aprim.2017.08.003. [Epub ahead of print] PubMed PMID: 29061311. 19: Nejashmikj VR, Stojkovska S, Topuzovska IK, Stavrikj K. Evidence Based Practice in Using Antibiotics for Acute Tonsillitis in Primary Care Practice. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2017 Sep 1;38(2):63-68. doi: 10.1515/prilozi-2017-0023. PubMed PMID: 28991775. 20: Størdal K, Mårild K, Blix HS. [Use of antibiotics in children during the period 2005 – 16]. Tidsskr Nor Laegeforen. 2017 Oct 2;137(18). doi: 10.4045/tidsskr.17.0272. Print 2017 Oct 3. Norwegian. PubMed PMID: 28972334.