MedKoo Cat#: 563851 | Name: Dimethoxy-etomidate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dimethoxy-etomidate is a nonhypnotic etomidate analog that potently inhibits steroidogenesis.

Chemical Structure

Dimethoxy-etomidate
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 563851

Name: Dimethoxy-etomidate

CAS#: NONE

Chemical Formula: C16H20N2O4

Exact Mass: 304.1423

Molecular Weight: 304.35

Elemental Analysis: C, 63.14; H, 6.62; N, 9.20; O, 21.03

Price and Availability

Size Price Availability Quantity
5mg USD 285.00 2 Weeks
25mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
Dimethoxy-etomidate; Dimethoxy etomidate; Dimethoxyetomidate
IUPAC/Chemical Name
Ethyl (R)-1-(1-(3,5-dimethoxy)phenylethyl)-1H-imidazole-5-carboxylate
InChi Key
JETTTZITBCWAQX-LLVKDONJSA-N
InChi Code
InChI=1S/C16H20N2O4/c1-5-22-16(19)15-9-17-10-18(15)11(2)12-6-13(20-3)8-14(7-12)21-4/h6-11H,5H2,1-4H3/t11-/m1/s1
SMILES Code
O=C(C1=CN=CN1[C@@H](C2=CC(OC)=CC(OC)=C2)C)OCC
Appearance
Oil
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Dimethoxy-etomidate is an analog of etomidate. It potently inhibits 11-beta-hydroxylase without GABAA receptor positive modulatory and sedative-hypnotic activities.

Preparing Stock Solutions

The following data is based on the product molecular weight 304.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: McGrath M, Ma C, Raines DE. Dimethoxy-etomidate: A Nonhypnotic Etomidate Analog that Potently Inhibits Steroidogenesis. J Pharmacol Exp Ther. 2018 Feb;364(2):229-237. doi: 10.1124/jpet.117.245332. Epub 2017 Dec 4. PubMed PMID: 29203576; PubMed Central PMCID: PMC5783534.