Hydroxy-PEG3-PFP ester | CAS# 1807537-40-1 | Hydroxy PEG Linker

MedKoo Cat#: 572440 | Name: Hydroxy-PEG3-PFP ester

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hydroxy-PEG3-PFP ester is a PEG derivative containing a hydroxyl group with a PFP ester group. It can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PFP esters have similar applications as the NHS esters, but are more stable in aqueous solution. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Chemical Structure

Hydroxy-PEG3-PFP ester

CAS#1807537-40-1

Theoretical Analysis

MedKoo Cat#: 572440

Name: Hydroxy-PEG3-PFP ester

CAS#: 1807537-40-1

Chemical Formula: C15H17F5O6

Exact Mass: 388.0945

Molecular Weight: 388.29

Elemental Analysis: C, 46.40; H, 4.41; F, 24.46; O, 24.72

Price and Availability

Size	Price	Availability	Quantity

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

No Data

Synonym

Hydroxy-PEG3-PFP ester

IUPAC/Chemical Name

perfluorophenyl 3-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)propanoate

InChi Key

MDIKFXKPNIRFLO-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H17F5O6/c16-10-11(17)13(19)15(14(20)12(10)18)26-9(22)1-3-23-5-7-25-8-6-24-4-2-21/h21H,1-8H2

SMILES Code

O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCO

Appearance

Solid powder

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 388.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Brown A, Patel S, Ward C, Lorenz A, Ortiz M, DuRoss A, Wieghardt F, Esch A, Otten EG, Heiser LM, Korolchuk VI, Sun C, Sarkar S, Sahay G. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750. doi: 10.1038/srep31750. PubMed PMID: 27572704; PubMed Central PMCID: PMC5004151. 2: Saifer MG, Williams LD, Sobczyk MA, Michaels SJ, Sherman MR. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46. doi: 10.1016/j.molimm.2013.07.014. Epub 2013 Nov 5. PubMed PMID: 24200843. 3: Garay RP, El-Gewely R, Armstrong JK, Garratty G, Richette P. Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents. Expert Opin Drug Deliv. 2012 Nov;9(11):1319-23. doi: 10.1517/17425247.2012.720969. Epub 2012 Aug 30. PubMed PMID: 22931049.