MedKoo Cat#: 127989 | Name: Werner Syndrome RecQ Helicase-IN-2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Werner syndrome RecQ helicase-IN-2 is an inhibitor of the DNA helicase Werner syndrome protein (WRN; IC50 = 100 nM).

Chemical Structure

Werner Syndrome RecQ Helicase-IN-2
Werner Syndrome RecQ Helicase-IN-2
CAS#2869954-51-6

Theoretical Analysis

MedKoo Cat#: 127989

Name: Werner Syndrome RecQ Helicase-IN-2

CAS#: 2869954-51-6

Chemical Formula: C32H34F3N9O5

Exact Mass: 681.2635

Molecular Weight: 681.68

Elemental Analysis: C, 56.38; H, 5.03; F, 8.36; N, 18.49; O, 11.74

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 950.00 2 Weeks
10mg USD 1,450.00 2 Weeks
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Synonym
Werner Syndrome RecQ Helicase-IN-2; Werner Syndrome RecQ Helicase Inhibitor 2; WS RecQ Helicase-IN-2; WS RecQ Helicase Inhibitor 2
IUPAC/Chemical Name
2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(5-hydroxy-6-methylpyrimidine-4-carbonyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)-N-(2-methyl-4-(trifluoromethyl)phenyl)acetamide
InChi Key
FHYSHYIPBJMLRM-UHFFFAOYSA-N
InChi Code
InChI=1S/C32H34F3N9O5/c1-4-23-26(41-9-11-42(12-10-41)29(47)25-27(46)19(3)36-17-37-25)30(48)44-31(39-28(40-44)20-7-13-49-14-8-20)43(23)16-24(45)38-22-6-5-21(15-18(22)2)32(33,34)35/h5-7,15,17,46H,4,8-14,16H2,1-3H3,(H,38,45)
SMILES Code
CC1=CC(C(F)(F)F)=CC=C1NC(CN(C2=NC(C3=CCOCC3)=NN24)C(CC)=C(N5CCN(C(C6=NC=NC(C)=C6O)=O)CC5)C4=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 681.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL