MedKoo Cat#: 593001 | Name: Dichlorisone acetate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dichlorisone acetate is a Glucocorticoid.

Chemical Structure

Dichlorisone acetate
Dichlorisone acetate
CAS#79-61-8 (acetate)

Theoretical Analysis

MedKoo Cat#: 593001

Name: Dichlorisone acetate

CAS#: 79-61-8 (acetate)

Chemical Formula: C23H28Cl2O5

Exact Mass: 454.1314

Molecular Weight: 455.37

Elemental Analysis: C, 60.67; H, 6.20; Cl, 15.57; O, 17.57

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
50mg USD 750.00 2 Weeks
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Synonym
Dichlorisone acetate; Diloderm; Dichlorisona; Cloriderm; Dermocid; Astroderm; Disoderm; Visoderm; NSC-759246; NSC759246; NSC 759246;
IUPAC/Chemical Name
(11beta)-21-(Acetyloxy)-9,11-dichloro-17-hydroxypregna-1,4-diene-3,20-dione
InChi Key
YNNURTVKPVJVEI-GSLJADNHSA-N
InChi Code
InChI=1S/C23H28Cl2O5/c1-13(26)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(27)6-8-20(14,2)23(17,25)18(24)11-21(16,22)3/h6,8,10,16-18,29H,4-5,7,9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1
SMILES Code
C[C@@]12[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(Cl)[C@@H](Cl)C2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 455.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Luo Y, Uboh CE, Soma LR, Guan FY, Rudy JA, Tsang DS. Simultaneous analysis of twenty-one glucocorticoids in equine plasma by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2005;19(10):1245-56. PubMed PMID: 15838928. 2: JEANDIDIER P. [DICHLORISONE ACETATE (VISODERM) IN LOCAL DERMATOLOGIC THERAPHY]. Ann Med Nancy. 1964 Aug-Sep;3:1062-5. French. PubMed PMID: 14229556. 3: WEREIDE K. [Plastic covering for corticosteroid salves in psoriasis. Therapeutic trials with fluocinolone acetonide, triamcinolone acetonide and dichlorisone acetate]. Tidsskr Nor Laegeforen. 1963 Jun 15;83:1034-7. Norwegian. PubMed PMID: 13999986.