Penupogenin | CAS#27526-87-0 | steroidal aglycone

MedKoo Cat#: 461807 | Name: Penupogenin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Penupogenin is a steroidal aglycone isolated from the roots of Cynanchum auriculatum.

Chemical Structure

Penupogenin

CAS#27526-87-0

Theoretical Analysis

MedKoo Cat#: 461807

Name: Penupogenin

CAS#: 27526-87-0

Chemical Formula: C30H40O7

Exact Mass: 512.2774

Molecular Weight: 512.64

Elemental Analysis: C, 70.29; H, 7.87; O, 21.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Penupogenin;

IUPAC/Chemical Name

(3S,8S,9R,10R,12R,13R,14R,17R)-3,8,14,17-tetrahydroxy-17-((S)-1-hydroxyethyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-12-yl cinnamate

InChi Key

CSSZPOBBUXFMAA-UPPMJXABSA-N

InChi Code

InChI=1S/C30H40O7/c1-19(31)28(34)15-16-30(36)27(28,3)24(37-25(33)10-9-20-7-5-4-6-8-20)18-23-26(2)13-12-22(32)17-21(26)11-14-29(23,30)35/h4-11,19,22-24,31-32,34-36H,12-18H2,1-3H3/b10-9+/t19-,22-,23+,24+,26-,27+,28-,29-,30+/m0/s1

SMILES Code

C[C@H](O)[C@@]1(O)CC[C@]2(O)[C@]3(O)CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])C[C@@H](OC(/C=C/C5=CC=CC=C5)=O)[C@]12C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 512.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Chen XL, Geng CA, Chen JJ. A Fragmentation Study of Six C21 Steroidal Aglycones by Electrospray Ionization Ion-Trap Time-of-Flight Tandem Mass Spectrometry. Nat Prod Commun. 2015 Dec;10(12):2053-8. PubMed PMID: 26882663. 2: Lu Y, Teng HL, Yang GZ, Mei ZN. Three new steroidal glycosides from the roots of Cynanchum auriculatum. Molecules. 2011 Feb 23;16(2):1901-9. doi: 10.3390/molecules16021901. PubMed PMID: 21346690. 3: Lee DU, Shin US, Huh K. Structure-activity relationships of gagaminine and its derivatives on the inhibition of hepatic aldehyde oxidase activity and lipid peroxidation. Arch Pharm Res. 1998 Jun;21(3):273-7. PubMed PMID: 9875443. 4: Warashina T, Noro T. Acylated-oxypregnane glycosides from the roots of Araujia sericifera. Chem Pharm Bull (Tokyo). 2003 Sep;51(9):1036-45. PubMed PMID: 12951444. 5: Mu QZ, Shen YM, Zhou QL, Wang SQ, Wu B, Zheng QT. Studies on the Constituents of Adelostemma gracillimum. Planta Med. 1992 Apr;58(2):200-4. PubMed PMID: 17226458.