RMI-18341 | CAS# 74850-10-5 | Biochemical

MedKoo Cat#: 576979 | Name: RMI-18341

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RMI-18341 is a Testosterone 5 alpha reductase inhibitor.

Chemical Structure

RMI-18341

CAS#74850-10-5

Theoretical Analysis

MedKoo Cat#: 576979

Name: RMI-18341

CAS#: 74850-10-5

Chemical Formula: C22H34N2O2

Exact Mass: 358.2620

Molecular Weight: 358.53

Elemental Analysis: C, 73.70; H, 9.56; N, 7.81; O, 8.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

MDL-18,341; MDL18341; MDL 18341; MDL-18341; RMI-18341; RMI 18341; RMI18341

IUPAC/Chemical Name

Pregnan-3-one, 4-diazo-21-hydroxy-20-methyl-, (5alpha,20R)-

InChi Key

MLPGZRVFTNWGPH-JIYYBXOBSA-N

InChi Code

InChI=1S/C22H34N2O2/c1-13(12-25)15-6-7-16-14-4-5-18-20(24-23)19(26)9-11-22(18,3)17(14)8-10-21(15,16)2/h13-18,25H,4-12H2,1-3H3/t13-,14-,15?,16-,17-,18-,21+,22+/m0/s1

SMILES Code

C[C@@H](CO)C1CC[C@H]2[C@@H]3CC[C@H]4C(=[N+]=[N-])C(=O)CC[C@]4(C)[C@H]3CC[C@]12C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 358.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Blohm TR, Metcalf BW, Laughlin ME, Sjoerdsma A, Schatzman GL. Inhibition of testosterone 5 alpha-reductase by a proposed enzyme-activated, active site-directed inhibitor. Biochem Biophys Res Commun. 1980 Jul 16;95(1):273-80. doi: 10.1016/0006-291x(80)90735-4. PMID: 7417256. 2. Blohm TR, Laughlin ME, Benson HD, Johnston JO, Wright CL, Schatzman GL, Weintraub PM. Pharmacological induction of 5 alpha-reductase deficiency in the rat: separation of testosterone-mediated and 5 alpha-dihydrotestosterone-mediated effects. Endocrinology. 1986 Sep;119(3):959-66. doi: 10.1210/endo-119-3-959. PMID: 3732173.