Sulfabromomethazine | CAS#116-45-0 | sulfamezathine derivative

MedKoo Cat#: 461673 | Name: Sulfabromomethazine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulfabromomethazine, also known as Bromosulfamethazine, NSC 5874, SN 3517, is a long-acting derivative of sulfamezathine that is used in the poultry, swine and cattle industries for the treatment of coccidiosis.

Chemical Structure

Sulfabromomethazine

CAS#116-45-0

Theoretical Analysis

MedKoo Cat#: 461673

Name: Sulfabromomethazine

CAS#: 116-45-0

Chemical Formula: C12H13BrN4O2S

Exact Mass: 355.9943

Molecular Weight: 357.22

Elemental Analysis: C, 40.35; H, 3.67; Br, 22.37; N, 15.68; O, 8.96; S, 8.97

Price and Availability

Size	Price	Availability
10mg	USD 150.00	Ready to ship
25mg	USD 250.00	Ready to ship
50mg	USD 450.00	Ready to ship
100mg	USD 825.00	Ready to ship
200mg	USD 1,550.00	Ready to ship

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Related CAS #

No Data

Synonym

5-Bromosulfamethazine; Bromosulfamethazine; NSC 5874; NSC-5874; NSC5874; SN 3517; SN-3517; SN3517; Sulfabrom ; Sulfabromomethazine;

IUPAC/Chemical Name

4-amino-N-(5-bromo-4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

InChi Key

KWXCNODTHBHSIQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H13BrN4O2S/c1-7-11(13)8(2)16-12(15-7)17-20(18,19)10-5-3-9(14)4-6-10/h3-6H,14H2,1-2H3,(H,15,16,17)

SMILES Code

O=S(C1=CC=C(N)C=C1)(NC2=NC(C)=C(Br)C(C)=N2)=O

Appearance

Orange to light red solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Certificate of Analysis

View CoA: current batch, Lot#YXM90828

QC Data

View QC data: current batch, Lot#YXM90828

Safety Data Sheet (SDS)

View Safety Data Sheet (SDS)

Instruction

View handling instruction

Biological target:

Sulfabromomethazine is a long-acting Sulfonamide that is used for the treatment of coccidiosis and various bacterial infections in poultry, swine, and cattle.

In vitro activity:

To be determined

In vivo activity:

To be determined

Preparing Stock Solutions

The following data is based on the product molecular weight 357.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

To be determined

In vitro protocol:

To be determined

In vivo protocol:

To be determined

1: STOWE CM, ARONSON AL, JOHNSON K. The pharmacology of sulfabromomethazine, a new long-acting sulfonamide, in cattle. Am J Vet Res. 1958 Apr;19(71):345-53. PubMed PMID: 13533757. 2: Unruh J, Schwartz DP, Barford RA. Quantitation of sulfamethazine in pork tissue by thin-layer chromatography. J AOAC Int. 1993 Mar-Apr;76(2):335-41. PubMed PMID: 8471859. 3: Goodspeed DP, Simpson RM, Ashworth RB, Shafer JW, Cook HR. Sensitive and specific gas-liquid chromatographic-spectrophotometric screening procedure for trace levels of five sulfonamides in liver, kidney, and muscle tissue. J Assoc Off Anal Chem. 1978 Sep;61(5):1050-3. PubMed PMID: 721719. 4: Fink DW, Martin RP, Blodinger J. Facile separation of sulfonamides from their degradates by liquid--liquid extraction. J Pharm Sci. 1978 Oct;67(10):1415-9. PubMed PMID: 702292. 5: Thomas MH, Soroka KE, Thomas SH. Quantitative thin layer chromatographic multi-sulfonamide screening procedure. J Assoc Off Anal Chem. 1983 Jul;66(4):881-3. PubMed PMID: 6885694. 6: Manuel AJ, Steller WA. Gas-liquid chromatographic determination of sulfamethazine in swine and cattle tissues. J Assoc Off Anal Chem. 1981 Jul;64(4):794-9. PubMed PMID: 7275892.