Flumioxazin | CAS#103361-09-7 | herbicide

MedKoo Cat#: 461648 | Name: Flumioxazin

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Flumioxazin is an herbicide registered for use in soybean and peanut.

Chemical Structure

Flumioxazin

CAS#103361-09-7

Theoretical Analysis

MedKoo Cat#: 461648

Name: Flumioxazin

CAS#: 103361-09-7

Chemical Formula: C19H15FN2O4

Exact Mass: 354.1016

Molecular Weight: 354.33

Elemental Analysis: C, 64.40; H, 4.27; F, 5.36; N, 7.91; O, 18.06

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 650.00	2 Weeks

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Related CAS #

No Data

Synonym

Flumioxazin; Flumioxazine; Sumisoya; S 53482; S-53482; S53482; V 53482; V53482; V-53482;

IUPAC/Chemical Name

2-(7-fluoro-3-oxo-4-(prop-2-yn-1-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione

InChi Key

FOUWCSDKDDHKQP-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2

SMILES Code

O=C1N(C2=C(F)C=C(OCC(N3CC#C)=O)C3=C2)C(C4=C1CCCC4)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 354.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Takaku T, Nagahori H, Sogame Y. Metabolism and physiologically based pharmacokinetic modeling of flumioxazin in pregnant animals. Toxicol Appl Pharmacol. 2014 Jun 15;277(3):242-9. doi: 10.1016/j.taap.2014.03.022. Epub 2014 Apr 6. PubMed PMID: 24717917. 2: Lu L, Yang L, Cai H, Zhang L, Lin Z, Guo L, Qiu B, Chen G. Determination of flumioxazin residue in food samples through a sensitive fluorescent sensor based on click chemistry. Food Chem. 2014 Nov 1;162:242-6. doi: 10.1016/j.foodchem.2014.04.061. Epub 2014 Apr 24. PubMed PMID: 24874382. 3: Park H, Kim J, Kwon E, Kim TH. Crystal structure of flumioxazin. Acta Crystallogr E Crystallogr Commun. 2015 Sep 17;71(Pt 10):o768. doi: 10.1107/S2056989015017223. eCollection 2015 Oct 1. PubMed PMID: 26594468; PubMed Central PMCID: PMC4647385. 4: Shibata A, Kodaka R, Fujisawa T, Katagi T. Degradation of flumioxazin in illuminated water-sediment systems. J Agric Food Chem. 2011 Oct 26;59(20):11186-95. doi: 10.1021/jf202542v. Epub 2011 Sep 29. PubMed PMID: 21919467. 5: Xie L, Zheng H, Ye W, Qiu S, Lin Z, Guo L, Qiu B, Chen G. Novel colorimetric molecular switch based on copper(I)-catalyzed azide-alkyne cycloaddition reaction and its application for flumioxazin detection. Analyst. 2013 Jan 21;138(2):688-92. doi: 10.1039/c2an36023c. PubMed PMID: 23188065. 6: Lu ZB, Wang Y, Yu P, Liu YL, Xu W. [Study on the residual dynamics of flumioxazin in soybean and soil]. Se Pu. 2000 Mar;18(2):145-7. Chinese. PubMed PMID: 12541592. 7: Ferrell JA, Vencill WK. Gas chromatographic/mass spectrometric determination of flumioxazin extracted from soil and water. J AOAC Int. 2004 Jan-Feb;87(1):56-9. PubMed PMID: 15084087. 8: Ferrell JA, Vencill WK. Flumioxazin soil persistence and mineralization in laboratory experiments. J Agric Food Chem. 2003 Jul 30;51(16):4719-21. PubMed PMID: 14705902. 9: Saladin G, Clément C, Magné C. Stress effects of flumioxazin herbicide on grapevine ( Vitis vinifera L.) grown in vitro. Plant Cell Rep. 2003 Aug;21(12):1221-7. Epub 2003 Jun 18. PubMed PMID: 12819925. 10: Alister C, Rojas S, Gómez P, Kogan M. Dissipation and movement of flumioxazin in soil at four field sites in Chile. Pest Manag Sci. 2008 May;64(5):579-83. doi: 10.1002/ps.1533. PubMed PMID: 18200616. 11: Ferrell JA, Vencill WK, Xia K, Grey TL. Sorption and desorption of flumioxazin to soil, clay minerals and ion-exchange resin. Pest Manag Sci. 2005 Jan;61(1):40-6. PubMed PMID: 15593072. 12: Bigot A, Fontaine F, Clément C, Vaillant-Gaveau N. Effect of the herbicide flumioxazin on photosynthetic performance of grapevine (Vitis vinifera L.). Chemosphere. 2007 Apr;67(6):1243-51. Epub 2006 Dec 20. PubMed PMID: 17184818. 13: Castro AJ, Saladin G, Bézier A, Mazeyrat-Gourbeyre F, Baillieul F, Clément C. The herbicide flumioxazin stimulates pathogenesis-related gene expression and enzyme activities in Vitis vinifera. Physiol Plant. 2008 Nov;134(3):453-63. doi: 10.1111/j.1399-3054.2008.01151.x. Epub 2008 Jul 31. PubMed PMID: 18636988. 14: Saladin G, Magné C, Clément C. Impact of flumioxazin herbicide on growth and carbohydrate physiology in Vitis vinifera L. Plant Cell Rep. 2003 Apr;21(8):821-7. Epub 2003 Mar 6. PubMed PMID: 12789529. 15: Kwon JW, Armbrust KL, Grey TL. Hydrolysis and photolysis of flumioxazin in aqueous buffer solutions. Pest Manag Sci. 2004 Sep;60(9):939-43. PubMed PMID: 15382510. 16: Geoffroy L, Frankart C, Eullaffroy P. Comparison of different physiological parameter responses in Lemna minor and Scenedesmus obliquus exposed to herbicide flumioxazin. Environ Pollut. 2004 Sep;131(2):233-41. PubMed PMID: 15234090. 17: Lin L, Ye G, Xie L, Lan F, Wu W, Jin B. [Determination of flumioxazin residue in foods using gas chromatography-mass spectrometry]. Se Pu. 2008 May;26(3):318-21. Chinese. PubMed PMID: 18724667. 18: Saladin G, Magné C, Clément C. Effects of flumioxazin herbicide on carbon nutrition of Vitis vinifera L. J Agric Food Chem. 2003 Jul 2;51(14):4017-22. PubMed PMID: 12822940. 19: Kawamura S, Kato T, Fantel AG. Close link between protoporphyrin IX accumulation and developmental toxicity induced by N-phenylimide herbicides in rats. Birth Defects Res B Dev Reprod Toxicol. 2014 Dec;101(6):429-37. doi: 10.1002/bdrb.21133. Epub 2014 Dec 4. PubMed PMID: 25475126. 20: Saladin G, Magné C, Clément C. Stress reactions in Vitis vinifera L. following soil application of the herbicide flumioxazin. Chemosphere. 2003 Oct;53(3):199-206. PubMed PMID: 12919779.