MedKoo Cat#: 572330 | Name: KUN 00675
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

KUN 00675, also known as N-methyl-N'-(Azido-PEG2-C5)-Cy5 is a PEG derivative containing a cyanine dye with excitation/emission maximum 649/667 nm as well as an azide group, which enables Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

KUN 00675
KUN 00675
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 572330

Name: KUN 00675

CAS#: NONE

Chemical Formula: C38H51ClN6O3

Exact Mass: 674.3711

Molecular Weight: 675.32

Elemental Analysis: C, 67.59; H, 7.61; Cl, 5.25; N, 12.44; O, 7.11

Price and Availability

Size Price Availability Quantity
1mg USD 380.00 2 Weeks
2mg USD 680.00 2 Weeks
5mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
N-methyl-N'-(Azido-PEG2-C5)-Cy5; KUN 00675; KUN-00675; KUN00675
IUPAC/Chemical Name
1-(6-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-6-oxohexyl)-3,3-dimethyl-2-((1E,3E)-5-((E)-1,3,3-trimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium chloride
InChi Key
KHXRWRZNDLAZDK-UHFFFAOYSA-N
InChi Code
InChI=1S/C38H50N6O3.ClH/c1-37(2)30-16-11-13-18-32(30)43(5)34(37)20-8-6-9-21-35-38(3,4)31-17-12-14-19-33(31)44(35)25-15-7-10-22-36(45)40-23-26-46-28-29-47-27-24-41-42-39;/h6,8-9,11-14,16-21H,7,10,15,22-29H2,1-5H3;1H
SMILES Code
CN(C(C=CC=C1)=C1C/2(C)C)C2=C\C=C\C=C\C3=[N+](CCCCCC(NCCOCCOCCN=[N+]=[N-])=O)C4=CC=CC=C4C3(C)C.[Cl-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, DMF, DCM
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Solubility: DMSO, DMF, DCM, low solubility in water Excitation maximum (nm): 649 Extinction coefficient and excitation maximum, Lmol-1cm-1: 232000 Emission maximum (nm): 667

Preparing Stock Solutions

The following data is based on the product molecular weight 675.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chen X, Zhang X, Wang HY, Chen Z, Wu FG. Subcellular Fate of a Fluorescent Cholesterol-Poly(ethylene glycol) Conjugate: An Excellent Plasma Membrane Imaging Reagent. Langmuir. 2016 Oct 4;32(39):10126-10135. Epub 2016 Sep 21. PubMed PMID: 27597442. 2: Chen G, Wang L, Cordie T, Vokoun C, Eliceiri KW, Gong S. Multi-functional self-fluorescent unimolecular micelles for tumor-targeted drug delivery and bioimaging. Biomaterials. 2015 Apr;47:41-50. doi: 10.1016/j.biomaterials.2015.01.006. Epub 2015 Feb 4. PubMed PMID: 25682159; PubMed Central PMCID: PMC4329508. 3: Ruan S, Qian J, Shen S, Chen J, Zhu J, Jiang X, He Q, Yang W, Gao H. Fluorescent carbonaceous nanodots for noninvasive glioma imaging after angiopep-2 decoration. Bioconjug Chem. 2014 Dec 17;25(12):2252-9. doi: 10.1021/bc500474p. Epub 2014 Nov 11. PubMed PMID: 25387274. 4: Ruan S, Wan J, Fu Y, Han K, Li X, Chen J, Zhang Q, Shen S, He Q, Gao H. PEGylated fluorescent carbon nanoparticles for noninvasive heart imaging. Bioconjug Chem. 2014 Jun 18;25(6):1061-8. doi: 10.1021/bc5001627. Epub 2014 May 22. PubMed PMID: 24852402. 5: Paira TK, Saha A, Banerjee S, Das T, Das P, Jana NR, Mandal TK. Fluorescent amphiphilic PEG-peptide-PEG triblock conjugate micelles for cell imaging. Macromol Biosci. 2014 Jul;14(7):929-35. doi: 10.1002/mabi.201400083. Epub 2014 Mar 31. PubMed PMID: 24687698. 6: Okuda T, Kobayashi Y, Yanamoto S, Okamoto H. PEG conjugation of a near-infrared fluorescent probe for noninvasive dual imaging of lung deposition and gene expression by pulmonary gene delivery. J Drug Target. 2012 Nov;20(9):801-12. doi: 10.3109/1061186X.2012.722639. Epub 2012 Sep 26. PubMed PMID: 23009266.