BX-513 HCl | CAS#1216540-18-9 | CCR1 receptor antagonist

MedKoo Cat#: 563566 | Name: BX-513 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BX-513 HCl is a selective CCR1 receptor antagonist.

Chemical Structure

BX-513 HCl

CAS#1216540-18-9

Theoretical Analysis

MedKoo Cat#: 563566

Name: BX-513 HCl

CAS#: 1216540-18-9

Chemical Formula: C28H30Cl2N2O

Exact Mass: 480.1735

Molecular Weight: 481.46

Elemental Analysis: C, 69.85; H, 6.28; Cl, 14.73; N, 5.82; O, 3.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

BX-513 hydrochloride; BX-513 HCl; BX 513 HCl; BX513 HCl; BX 513 hydrochloride; BX513 hydrochloride; VUF 2274; VUF-2274; VUF2274;

IUPAC/Chemical Name

5-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile hydrochloride

InChi Key

SSZWNUGWOGONQJ-UHFFFAOYSA-N

InChi Code

InChI=1S/C28H29ClN2O.ClH/c29-26-14-12-25(13-15-26)28(32)17-20-31(21-18-28)19-7-16-27(22-30,23-8-3-1-4-9-23)24-10-5-2-6-11-24;/h1-6,8-15,32H,7,16-21H2;1H

SMILES Code

N#CC(C1=CC=CC=C1)(C2=CC=CC=C2)CCCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 481.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Di Prisco S, Merega E, Pittaluga A. Functional adaptation of presynaptic chemokine receptors in EAE mouse central nervous system. Synapse. 2014 Nov;68(11):529-35. doi: 10.1002/syn.21774. Epub 2014 Aug 19. PubMed PMID: 25092801. 2: Di Prisco S, Summa M, Chellakudam V, Rossi PI, Pittaluga A. RANTES-mediated control of excitatory amino acid release in mouse spinal cord. J Neurochem. 2012 May;121(3):428-37. doi: 10.1111/j.1471-4159.2012.07720.x. Epub 2012 Mar 21. PubMed PMID: 22385043.