MedKoo Cat#: 598978 | Name: Fentin acetate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fentin acetate is an organotin compound. Triphenyltin Acetate much like its hydroxide analogue is used as a fungicide and antifeeding compound for insect control. Recent studies show that Triphenyltin Acetate may have adverse effects on the reproductive and immune systems and may disrupt the endocrine system.

Chemical Structure

Fentin acetate
Fentin acetate
CAS#900-95-8

Theoretical Analysis

MedKoo Cat#: 598978

Name: Fentin acetate

CAS#: 900-95-8

Chemical Formula: C20H18O2Sn

Exact Mass: 410.0329

Molecular Weight: 409.07

Elemental Analysis: C, 58.72; H, 4.44; O, 7.82; Sn, 29.02

Price and Availability

Size Price Availability Quantity
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Fentin acetate; GC 6936; GC-6936; GC6936; Suzu; Acetoxytriphenyltin; AI3-25208; HOE-2824;
IUPAC/Chemical Name
triphenylstannyl acetate
InChi Key
WDQNIWFZKXZFAY-UHFFFAOYSA-M
InChi Code
InChI=1S/3C6H5.C2H4O2.Sn/c3*1-2-4-6-5-3-1;1-2(3)4;/h3*1-5H;1H3,(H,3,4);/q;;;;+1/p-1
SMILES Code
CC(O[Sn](c1ccccc1)(c2ccccc2)c3ccccc3)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 409.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cotta-Ramusino M, Doci A. Acute toxicity of Brestan and fentin acetate on some freshwater organisms. Bull Environ Contam Toxicol. 1987 Apr;38(4):647-52. PubMed PMID: 3567403. 2: Ma J, Lin F, Qin W, Wang P. Differential response of four cyanobacterial and green algal species to triazophos, fentin acetate, and ethephon. Bull Environ Contam Toxicol. 2004 Nov;73(5):890-7. PubMed PMID: 15669734. 3: van den Broek HH, Hermes GB, Goewie CE. Determination of fentin residues in potatoes and celery. Analyst. 1988 Aug;113(8):1237-9. PubMed PMID: 3232835. 4: Giavini E, Prati M, Vismara C. Effects of triphenyltin acetate on pregnancy in the rat. Bull Environ Contam Toxicol. 1980 Jun;24(6):936-9. PubMed PMID: 7397432. 5: Manzo L, Richelmi P, Sabbioni E, Pietra R, Bono F, Guardia L. Poisoning by triphenyltin acetate. Report of two cases and determination of tin in blood and urine by neutron activation analysis. Clin Toxicol. 1981 Nov;18(11):1343-53. PubMed PMID: 7341061. 6: Dacasto M, Cornaglia E, Nebbia C, Bollo E. Triphenyltin acetate-induced cytotoxicity and CD4(+) and CD8(+) depletion in mouse thymocyte primary cultures. Toxicology. 2001 Dec 28;169(3):227-38. PubMed PMID: 11718962. 7: Colosio C, Tomasini M, Cairoli S, Foà V, Minoia C, Marinovich M, Galli CL. Occupational triphenyltin acetate poisoning: a case report. Br J Ind Med. 1991 Feb;48(2):136-9. PubMed PMID: 1825604; PubMed Central PMCID: PMC1035334. 8: KLIMMER OR. [Triphenyltin acetate--a contribution to the toxicology of organic tin compounds]. Arzneimittelforschung. 1963 Jun;13:432-6. German. PubMed PMID: 14033507. 9: Lin TJ, Hung DZ, Kao CH, Hu WH, Yang DY. Unique cerebral dysfunction following triphenyltin acetate poisoning. Hum Exp Toxicol. 1998 Jul;17(7):403-5. PubMed PMID: 9726537. 10: Strmac M, Braunbeck T. Effects of triphenyltin acetate on survival, hatching success, and liver ultrastructure of early life stages of zebrafish (Danio rerio). Ecotoxicol Environ Saf. 1999 Sep;44(1):25-39. PubMed PMID: 10499986. 11: de Haas EM, Roessink I, Verbree B, Koelmans AA, Kraak MH, Admiraal W. Influence of sediment quality on the responses of benthic invertebrates after treatment with the fungicide triphenyltin acetate. Environ Toxicol Chem. 2005 May;24(5):1133-9. PubMed PMID: 16110991. 12: HEROK J, GOETTE H. [RADIOMETRIC ANALYSIS OF TRIPHENYL TIN ACETATE IN THE METABOLISM OF PLANTS AND ANIMALS]. Int J Appl Radiat Isot. 1963 Oct;14:461-79. German. PubMed PMID: 14074302. 13: Nebbia C, Ceppa L, Dacasto M, Carletti M. Triphenyltin acetate-mediated in vitro inactivation of rat liver cytochrome P-450. J Toxicol Environ Health A. 1999 Mar 26;56(6):433-47. PubMed PMID: 10096365. 14: Bollo E, Guglielmino R, Sant S, Pregel P, Riondato F, Miniscalco B, Cornaglia E, Nebbia C, Dacasto M. Biochemical, ultrastructural and molecular characterization of the triphenyltin acetate (TPTA)-induced apoptosis in primary cultures of mouse thymocytes. Cell Biol Toxicol. 2006 Jul;22(4):275-84. Epub 2006 Jun 26. PubMed PMID: 16802106. 15: Bollo E, Dacasto M, Cornaglia E. Apoptosis and CD4+, CD8+ lymphocyte depletion following triphenyltin acetate (TPTA) exposure in mice thymic primary culture. Eur J Histochem. 1997;41 Suppl 2:171-2. PubMed PMID: 9859834. 16: Yen JH, Tsai CC, Su CC, Wang YS. Environmental dissipation of fungicide triphenyltin acetate and its potential as a groundwater contaminant. Ecotoxicol Environ Saf. 2001 Jun;49(2):164-70. PubMed PMID: 11386730. 17: Dacasto M, Nebbia C, Bollo E. Triphenyltin acetate (TPTA)-induced cytotoxicity to mouse thymocytes. Pharmacol Res. 1994 Feb-Mar;29(2):179-86. PubMed PMID: 8058591. 18: Noda T, Morita S, Yamano T, Shimizu M, Yamada A. Effects of triphenyltin acetate on pregnancy in rats by oral administration. Toxicol Lett. 1991 Apr;56(1-2):207-12. PubMed PMID: 2017780. 19: Bollo E, Ceppa L, Cornaglia E, Nebbia C, Biolatti B, Dacasto M. Triphenyltin acetate toxicity: a biochemical and ultrastructural study on mouse thymocytes. Hum Exp Toxicol. 1996 Mar;15(3):219-25. PubMed PMID: 8839209. 20: Chao JS, Wei LY, Huang MC, Liang SC, Chen HH. Genotoxic effects of triphenyltin acetate and triphenyltin hydroxide on mammalian cells in vitro and in vivo. Mutat Res. 1999 Jul 21;444(1):167-74. PubMed PMID: 10477351.