1: Li D, Zhang SZ, Yao YH, Xiang Y, Ma XY, Wei XL, Yan HT, Liu XY. Sigma-1 receptor agonist increases axon outgrowth of hippocampal neurons via voltage-gated calcium ions channels. CNS Neurosci Ther. 2017 Dec;23(12):930-939. doi: 10.1111/cns.12768. Epub 2017 Oct 8. PubMed PMID: 28990373.
2: Di T, Zhang S, Hong J, Zhang T, Chen L. Hyperactivity of Hypothalamic-Pituitary-Adrenal Axis Due to Dysfunction of the Hypothalamic Glucocorticoid Receptor in Sigma-1 Receptor Knockout Mice. Front Mol Neurosci. 2017 Sep 6;10:287. doi: 10.3389/fnmol.2017.00287. eCollection 2017. PubMed PMID: 28932185; PubMed Central PMCID: PMC5592243.
3: Chen T, Tanaka M, Wang Y, Sha S, Furuya K, Chen L, Sokabe M. Neurosteroid dehydroepiandrosterone enhances activity and trafficking of astrocytic GLT-1 via σ(1) receptor-mediated PKC activation in the hippocampal dentate gyrus of rats. Glia. 2017 Sep;65(9):1491-1503. doi: 10.1002/glia.23175. Epub 2017 Jun 5. PubMed PMID: 28581152.
4: Lenart L, Hodrea J, Hosszu A, Koszegi S, Zelena D, Balogh D, Szkibinszkij E, Veres-Szekely A, Wagner L, Vannay A, Szabo AJ, Fekete A. The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats. Psychopharmacology (Berl). 2016 Apr;233(7):1269-78. doi: 10.1007/s00213-016-4209-x. Epub 2016 Jan 26. PubMed PMID: 26809458.
5: Tanimukai H, Kudo T. Fluvoxamine alleviates paclitaxel-induced neurotoxicity. Biochem Biophys Rep. 2015 Sep 25;4:202-206. doi: 10.1016/j.bbrep.2015.09.014. eCollection 2015 Dec. PubMed PMID: 29124205; PubMed Central PMCID: PMC5668922.
6: Hong J, Sha S, Zhou L, Wang C, Yin J, Chen L. Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons. Cell Death Dis. 2015 Jul 23;6:e1832. doi: 10.1038/cddis.2015.194. PubMed PMID: 26203861; PubMed Central PMCID: PMC4650739.
7: Yin J, Sha S, Chen T, Wang C, Hong J, Jie P, Zhou R, Li L, Sokabe M, Chen L. Sigma-1 (σ₁) receptor deficiency reduces β-amyloid(25-35)-induced hippocampal neuronal cell death and cognitive deficits through suppressing phosphorylation of the NMDA receptor NR2B. Neuropharmacology. 2015 Feb;89:215-24. doi: 10.1016/j.neuropharm.2014.09.027. Epub 2014 Oct 5. PubMed PMID: 25286118.
8: Sánchez-Blázquez P, Rodríguez-Muñoz M, Herrero-Labrador R, Burgueño J, Zamanillo D, Garzón J. The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases. Int J Neuropsychopharmacol. 2014 Dec;17(12):1943-55. doi: 10.1017/S1461145714000029. Epub 2014 Jan 31. PubMed PMID: 24485144.
9: Yang R, Chen L, Wang H, Xu B, Tomimoto H, Chen L. Anti-amnesic effect of neurosteroid PREGS in Aβ25-35-injected mice through σ1 receptor- and α7nAChR-mediated neuroprotection. Neuropharmacology. 2012 Nov;63(6):1042-50. doi: 10.1016/j.neuropharm.2012.07.035. Epub 2012 Jul 31. PubMed PMID: 22884465.
10: Li L, Xu B, Zhu Y, Chen L, Sokabe M, Chen L. DHEA prevents Aβ25-35-impaired survival of newborn neurons in the dentate gyrus through a modulation of PI3K-Akt-mTOR signaling. Neuropharmacology. 2010 Sep-Oct;59(4-5):323-33. doi: 10.1016/j.neuropharm.2010.02.009. Epub 2010 Feb 16. PubMed PMID: 20167228.
11: Li Z, Cui S, Zhang Z, Zhou R, Ge Y, Sokabe M, Chen L. DHEA-neuroprotection and -neurotoxicity after transient cerebral ischemia in rats. J Cereb Blood Flow Metab. 2009 Feb;29(2):287-96. doi: 10.1038/jcbfm.2008.118. Epub 2008 Oct 15. PubMed PMID: 18854841.
12: Cai W, Zhu Y, Furuya K, Li Z, Sokabe M, Chen L. Two different molecular mechanisms underlying progesterone neuroprotection against ischemic brain damage. Neuropharmacology. 2008 Aug;55(2):127-38. doi: 10.1016/j.neuropharm.2008.04.023. Epub 2008 May 10. PubMed PMID: 18572204.
13: Li Z, Zhou R, Cui S, Xie G, Cai W, Sokabe M, Chen L. Dehydroepiandrosterone sulfate prevents ischemia-induced impairment of long-term potentiation in rat hippocampal CA1 by up-regulating tyrosine phosphorylation of NMDA receptor. Neuropharmacology. 2006 Oct;51(5):958-66. Epub 2006 Aug 8. PubMed PMID: 16895729.
14: Chen L, Dai XN, Sokabe M. Chronic administration of dehydroepiandrosterone sulfate (DHEAS) primes for facilitated induction of long-term potentiation via sigma 1 (sigma1) receptor: optical imaging study in rat hippocampal slices. Neuropharmacology. 2006 Mar;50(3):380-92. Epub 2005 Dec 20. PubMed PMID: 16364377.
15: Colabufo NA, Berardi F, Contino M, Niso M, Abate C, Perrone R, Tortorella V. Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines. Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):106-13. Epub 2004 Jul 31. PubMed PMID: 15322732.
16: Takebayashi M, Hayashi T, Su TP. Nerve growth factor-induced neurite sprouting in PC12 cells involves sigma-1 receptors: implications for antidepressants. J Pharmacol Exp Ther. 2002 Dec;303(3):1227-37. PubMed PMID: 12438547.