MedKoo Cat#: 461518 | Name: RU-39411

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RU-39411 is a steroidal anti-estrogen.

Chemical Structure

RU-39411
RU-39411
CAS#120382-04-9

Theoretical Analysis

MedKoo Cat#: 461518

Name: RU-39411

CAS#: 120382-04-9

Chemical Formula: C28H37NO3

Exact Mass: 435.2773

Molecular Weight: 435.60

Elemental Analysis: C, 77.20; H, 8.56; N, 3.22; O, 11.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
RU-39411; RU 39411; RU39411;
IUPAC/Chemical Name
(8S,9R,11S,13S,14S,17S)-11-(4-(2-(dimethylamino)ethoxy)phenyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
InChi Key
VBPPJMXMMHJPDP-JZFZMOLRSA-N
InChi Code
InChI=1S/C28H37NO3/c1-28-17-24(18-4-8-21(9-5-18)32-15-14-29(2)3)27-22-11-7-20(30)16-19(22)6-10-23(27)25(28)12-13-26(28)31/h4-5,7-9,11,16,23-27,30-31H,6,10,12-15,17H2,1-3H3/t23-,24+,25-,26-,27+,28-/m0/s1
SMILES Code
C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])[C@@H](C5=CC=C(OCCN(C)C)C=C5)C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 435.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hanson RN, Hua E, Labaree D, Hochberg RB, Proffitt K, Essigmann JM, Croy RG. Convergent synthesis of a steroidal antiestrogen-mitomycin C hybrid using "click" chemistry. Org Biomol Chem. 2012 Nov 14;10(42):8501-8. doi: 10.1039/c2ob25902h. Epub 2012 Sep 25. PubMed PMID: 23007562; PubMed Central PMCID: PMC3519291. 2: Jain S, Saxena D, Kumar PG, Koide SS, Laloraya M. Effect of estradiol and selected antiestrogens on pro- and antioxidant pathways in mammalian uterus. Contraception. 1999 Aug;60(2):111-8. PubMed PMID: 10592859. 3: Li XJ, Yu H, Koide SS. Effect of mifepristone and antiestrogens on uterine PGF2 alpha and PGE2 concentrations in ovariectomized and pregnant rats. Prostaglandins. 1997 Mar;53(3):187-97. PubMed PMID: 9206800. 4: Dao B, Vanage G, Marshall A, Bardin CW, Koide SS. Anti-implantation activity of antiestrogens and mifepristone. Contraception. 1996 Oct;54(4):253-8. PubMed PMID: 8922879.