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MedKoo Cat#: 598859 | Name: Ligustrin A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ligustrin A is a bioactive chemical.

Chemical Structure

Ligustrin A
Ligustrin A
CAS#83145-46-4

Theoretical Analysis

MedKoo Cat#: 598859

Name: Ligustrin A

CAS#: 83145-46-4

Chemical Formula: C83H146O10

Exact Mass: 1303.0916

Molecular Weight: 1304.07

Elemental Analysis: C, 76.45; H, 11.29; O, 12.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ligustrin A; Syringin;
IUPAC/Chemical Name
(3S,4R,5R,6S)-6-(((4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-2,2,6a,6b,9,9,12a-heptamethyl-10-(palmitoyloxy)-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carbonyl)oxy)-5-hydroxytetrahydro-2H-pyran-3,4-diyl dipalmitate
InChi Key
VXOAPJVJWUAJCE-HEFYQJOPSA-N
InChi Code
InChI=1S/C83H146O10/c1-11-14-17-20-23-26-29-32-35-38-41-44-47-50-71(84)90-67-64-89-76(74(87)75(67)92-73(86)52-49-46-43-40-37-34-31-28-25-22-19-16-13-3)93-77(88)83-61-59-78(4,5)63-66(83)65-53-54-69-80(8)57-56-70(79(6,7)68(80)55-58-82(69,10)81(65,9)60-62-83)91-72(85)51-48-45-42-39-36-33-30-27-24-21-18-15-12-2/h53,66-70,74-76,87H,11-52,54-64H2,1-10H3/t66-,67-,68-,69+,70+,74+,75-,76-,80+,81+,82+,83-/m0/s1
SMILES Code
CC1(C)[C@H](OC(CCCCCCCCCCCCCCC)=O)CC[C@@]2(C)[C@H]3CC=C4[C@@H]5CC(C)(C)CC[C@@](C(O[C@H]6[C@@H]([C@H]([C@H](CO6)OC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCC)=O)O)=O)5CC[C@](C)4[C@@](C)3CC[C@@H]12
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,304.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Che CT, Wong MS. Ligustrum lucidum and its Constituents: A Mini-Review on the Anti-Osteoporosis Potential. Nat Prod Commun. 2015 Dec;10(12):2189-94. Review. PubMed PMID: 26882695. 2: Mani BM, Huerta-Ocampo JA, Garcia-Sanchez JR, Barrera-Pacheco A, de la Rosa AP, Teran LM. Identification of Ligustrum lucidum pollen allergens using a proteomics approach. Biochem Biophys Res Commun. 2015 Dec 25;468(4):788-92. doi: 10.1016/j.bbrc.2015.11.033. Epub 2015 Nov 10. PubMed PMID: 26562528. 3: Wu X, He W, Zhang H, Li Y, Liu Z, He Z. Acteoside: a lipase inhibitor from the Chinese tea Ligustrum purpurascens kudingcha. Food Chem. 2014 Jan 1;142:306-10. doi: 10.1016/j.foodchem.2013.07.071. Epub 2013 Jul 25. PubMed PMID: 24001846. 4: Hernández Á, Falcó JV. Quantitative parameters and ecological implications of a specialized tritrophic interaction involving a seed-feeding tortricid, Pseudargyrotoza conwagana, a braconid parasitoid, Bracon otiosus, and the wild privet, Ligustrum vulgare. J Insect Sci. 2014;14:128. doi: 10.1093/jis/14.1.128. PubMed PMID: 25368072; PubMed Central PMCID: PMC4222312. 5: Czerwińska ME, Ziarek M, Bazylko A, Osińska E, Kiss AK. Quantitative Determination of Secoiridoids and Phenylpropanoids in Different Extracts of Ligustrum Vulgare L. Leaves by a Validated HPTLC-Photodensitometry Method. Phytochem Anal. 2015 Jul-Aug;26(4):253-60. doi: 10.1002/pca.2558. Epub 2015 Feb 19. PubMed PMID: 25693970. 6: Liu Q, Kim SH, Kim SB, Jo YH, Kim ES, Hwang BY, Oh K, Lee MK. Anti-obesity effect of (8-E)-niizhenide, a secoiridoid from Ligustrum lucidum, in high-fat diet-induced obese mice. Nat Prod Commun. 2014 Oct;9(10):1399-401. PubMed PMID: 25522524. 7: Igori D, Lim S, Zhao F, Baek D, Park JM, Cho HS, Kim HS, Kwon SY, Moon JS. The complete sequence and genome organization of ligustrum virus A, a novel carlavirus. Arch Virol. 2016 Dec;161(12):3593-3596. Epub 2016 Sep 10. PubMed PMID: 27614753. 8: Hu LX, Chen Y, He ZS, Zou ZW, Xia B. Demographic analysis of the fitness of Problepsis superans (Lepidoptera: Geometridae) feeding on three ligustrum (Lamiales: Oleaceae) species. J Econ Entomol. 2014 Jun;107(3):1045-54. PubMed PMID: 25026663. 9: Czerwińska ME, Granica S, Kiss AK. Effects of an aqueous extract from leaves of Ligustrum vulgare on mediators of inflammation in a human neutrophils model. Planta Med. 2013 Jul;79(11):924-32. doi: 10.1055/s-0032-1328718. Epub 2013 Jul 3. PubMed PMID: 23824550. 10: Hu B, Du Q, Deng S, An HM, Pan CF, Shen KP, Xu L, Wei MM, Wang SS. Ligustrum lucidum Ait. fruit extract induces apoptosis and cell senescence in human hepatocellular carcinoma cells through upregulation of p21. Oncol Rep. 2014 Sep;32(3):1037-42. doi: 10.3892/or.2014.3312. Epub 2014 Jul 7. PubMed PMID: 25017491. 11: Macková A, Mucaji P, Widowitz U, Bauer R. In vitro anti-inflammatory activity of Ligustrum vulgare extracts and their analytical characterization. Nat Prod Commun. 2013 Nov;8(11):1509-12. PubMed PMID: 24427928. 12: Guo N, Yu Y, Ablajan K, Li L, Fan B, Peng J, Yan H, Ma F, Nie Y. Seasonal variations in metabolite profiling of the fruits of Ligustrum lucidum Ait. Rapid Commun Mass Spectrom. 2011 Jun 30;25(12):1701-14. doi: 10.1002/rcm.5036. PubMed PMID: 21598330. 13: Yu ZL, Zeng WC. Antioxidant, antibrowning, and cytoprotective activities of Ligustrum robustum (Rxob.) Blume extract. J Food Sci. 2013 Sep;78(9):C1354-62. doi: 10.1111/1750-3841.12224. Epub 2013 Aug 7. PubMed PMID: 23924383. 14: Yang DM, Ouyang MA, Lv SQ. Combined treatment of Pseudomonas aeruginosa PA01 biofilm formation with the water-soluble extract of Ligustrum sinense and gentamicin sulphate. J Environ Biol. 2013 Apr;34(2 Spec No):451-7. PubMed PMID: 24620617. 15: Zhang Y, Liu L, Gao J, Wu C, Han L, Liu E, Shi P, Gao X, Wang T. New secoiridoids from the fruits of Ligustrum lucidum Ait with triglyceride accumulation inhibitory effects. Fitoterapia. 2013 Dec;91:107-112. doi: 10.1016/j.fitote.2013.08.022. Epub 2013 Aug 31. PubMed PMID: 24001714. 16: Mučaji P, Záhradníková A, Bezáková L, Cupáková M, Rauová D, Nagy M. HPLC determination of antilipoxygenase activity of a water infusion of Ligustrum vulgare L. leaves and some of its constituents. Molecules. 2011 Sep 28;16(10):8198-208. doi: 10.3390/molecules16108198. PubMed PMID: 21959294. 17: Song X, Li CY, Zeng Y, Wu HQ, Huang Z, Zhang J, Hong RS, Chen XX, Wang LY, Hu XP, Su WW, Li Y, He ZD. Immunomodulatory effects of crude phenylethanoid glycosides from Ligustrum purpurascens. J Ethnopharmacol. 2012 Dec 18;144(3):584-91. doi: 10.1016/j.jep.2012.09.047. Epub 2012 Oct 11. PubMed PMID: 23064286. 18: Wang H, Shi H, Wang Y. Effects of weather, time, and pollution level on the amount of particulate matter deposited on leaves of Ligustrum lucidum. ScientificWorldJournal. 2015;2015:935942. doi: 10.1155/2015/935942. Epub 2015 Jan 1. PubMed PMID: 25685849; PubMed Central PMCID: PMC4313054. 19: Aoki S, Honda Y, Kikuchi T, Miura T, Sugawara R, Yaoita Y, Kikuchi M, Machida K. Six new secoiridoids from the dried fruits of Ligustrum lucidum. Chem Pharm Bull (Tokyo). 2012;60(2):251-6. PubMed PMID: 22293486. 20: Xie ZM, Zhou T, Liao HY, Ye Q, Liu S, Qi L, Huang J, Zuo HJ, Pei XF. Effects of Ligustrum robustum on gut microbes and obesity in rats. World J Gastroenterol. 2015 Dec 14;21(46):13042-54. doi: 10.3748/wjg.v21.i46.13042. PubMed PMID: 26676281; PubMed Central PMCID: PMC4674722.