MedKoo Cat#: 563532 | Name: WWL123
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

WWL123 is a brain-penetrant inhibitor of α/β-hydrolase domain-containing protein 6 (ABHD6), exhibiting an IC₅₀ of 0.43 µM. It demonstrates over 10-fold selectivity for ABHD6 compared to a panel of approximately 35 other serine hydrolases.

Chemical Structure

WWL123
WWL123
CAS#1338574-83-6

Theoretical Analysis

MedKoo Cat#: 563532

Name: WWL123

CAS#: 1338574-83-6

Chemical Formula: C28H24N2O3

Exact Mass: 436.1787

Molecular Weight: 436.51

Elemental Analysis: C, 77.04; H, 5.54; N, 6.42; O, 11.00

Price and Availability

Size Price Availability Quantity
10mg USD 550.00 2 Weeks
50mg USD 1,350.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
WWL123; WWL-123; WWL 123;
IUPAC/Chemical Name
4'-carbamoyl-[1,1'-biphenyl]-4-yl ([1,1'-biphenyl]-3-ylmethyl)(methyl)carbamate
InChi Key
UUJGYRHAOHORFC-UHFFFAOYSA-N
InChi Code
InChI=1S/C28H24N2O3/c1-30(19-20-6-5-9-25(18-20)21-7-3-2-4-8-21)28(32)33-26-16-14-23(15-17-26)22-10-12-24(13-11-22)27(29)31/h2-18H,19H2,1H3,(H2,29,31)
SMILES Code
O=C(OC1=CC=C(C2=CC=C(C(N)=O)C=C2)C=C1)N(CC3=CC(C4=CC=CC=C4)=CC=C3)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 436.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhong P, Pan B, Gao XP, Blankman JL, Cravatt BF, Liu QS. Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum. J Physiol. 2011 Oct 15;589(Pt 20):4847-55. doi: 10.1113/jphysiol.2011.215509. Epub 2011 Sep 12. PubMed PMID: 21911610; PubMed Central PMCID: PMC3224879.