dTAG-13 is extremely selective for degradation of FKBP12F36V fusion chimeras. IP administration of dTAG-13 (25 mg/kg) significantly diminished bioluminescent signal in a disseminated model of leukemia (MV4;11 cells expressing luciferase-FKBP12F36V) in 4 h (Nabet et al.).
MedKoo Cat#: 465036
Name: dTAG-13
CAS#: 2064175-41-1
Chemical Formula: C57H68N4O15
Exact Mass: 1048.4681
Molecular Weight: 1049.18
Elemental Analysis: C, 65.25; H, 6.53; N, 5.34; O, 22.87
The following data is based on the product molecular weight 1,049.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
