Synonym
                                        311C90; Zolmitriptan; NSC 760383; NSC-760383; NSC760383; 
                                     
                                    
                                        IUPAC/Chemical Name
                                        (4S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
                                     
                                    
                                        InChi Key
                                        ULSDMUVEXKOYBU-ZDUSSCGKSA-N
                                     
                                    
                                        InChi Code
                                        InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
                                     
                                    
                                        SMILES Code
                                        O=C1OC[C@H](CC2=CC3=C(NC=C3CCN(C)C)C=C2)N1
                                     
                                    
                                    
                                        Purity
                                        >98% (or refer to the Certificate of Analysis)
                                     
                                    
                                        Shipping Condition
                                        Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                                     
                                    
                                        Storage Condition
                                        Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                                     
                                    
                                        Solubility
                                        Soluble in DMSO, not in water
                                     
                                    
                                        Shelf Life
                                        >2 years if stored properly
                                     
                                    
                                        Drug Formulation
                                        This drug may be formulated in DMSO
                                     
                                    
                                        Stock Solution Storage
                                        0 - 4 C for short term (days to weeks), or -20 C for long term (months).
                                     
                                    
                                        HS Tariff Code
                                        2934.99.9001
                                     
                                    
                                 
                             
                            
                                                        
                                                                
                                    Preparing Stock Solutions
                                    
                                        The following data is based on the
                                        product
                                        molecular weight
                                        287.36
                                        Batch specific molecular weights may vary
                                        from batch to batch
                                        due to the degree of hydration, which will
                                        affect the solvent
                                        volumes required to prepare stock solutions.
                                    
                                    
                                    
                                        
                                            
                                            
                                                | Concentration / Solvent Volume / Mass | 
                                                1 mg | 
                                                5 mg | 
                                                10 mg | 
                                            
                                            
                                            
                                            
                                                | 1 mM | 
                                                1.15 mL | 
                                                5.76 mL | 
                                                11.51 mL | 
                                            
                                            
                                                | 5 mM | 
                                                0.23 mL | 
                                                1.15 mL | 
                                                2.3 mL | 
                                            
                                            
                                                | 10 mM | 
                                                0.12 mL | 
                                                0.58 mL | 
                                                1.15 mL | 
                                            
                                            
                                                | 50 mM | 
                                                0.02 mL | 
                                                0.12 mL | 
                                                0.23 mL | 
                                            
                                            
                                        
                                     
                                 
                                                             
                            
                            
                                
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2: Tepper SJ, Chen S, Reidenbach F, Rapoport AM. Intranasal zolmitriptan for the  treatment of acute migraine. Headache. 2013 Sep;53 Suppl 2:62-71. doi: 10.1111/head.12181. Review. PubMed PMID: 24024604.
3: Peterlin BL, Rapoport AM. Clinical pharmacology of the serotonin receptor agonist, zolmitriptan. Expert Opin Drug Metab Toxicol. 2007 Dec;3(6):899-911. Review. PubMed PMID: 18028032.
4: Pacheco-Coronado R, McMullan PW, Galbut BH, Galbut EJ, Snell J, Schaer GL, Kavinsky CJ. Myocardial infarction after taking zolmitriptan. Yale J Biol Med. 2005 May;78(3):147-50. Review. PubMed PMID: 16464313; PubMed Central PMCID: PMC2259142.
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7: Gawel M, Worthington I. Intranasal zolmitriptan. Expert Opin Pharmacother. 2005 Jun;6(6):1019-24. Review. PubMed PMID: 15952929.
8: Rapoport AM, Bigal ME, Tepper SJ, Sheftell FD. Zolmitriptan (Zomig). Expert Rev Neurother. 2004 Jan;4(1):33-41. Review. PubMed PMID: 15853613.
9: Boutilier AS, Gardner DM. Reassessing the contraindication of zolmitriptan and serotonin reuptake inhibitors: an evidence-based pharmacotherapeutic case report. J Clin Pharm Ther. 2003 Feb;28(1):69-72. Review. PubMed PMID: 12605621.
10: Goadsby PJ, Boes CJ. Zolmitriptan: differences from sumatriptan. Curr Med Res Opin. 2001;17 Suppl 1:s46-50. Review. PubMed PMID: 12463277.
11: Dowson AJ, Charlesworth B. Review of zolmitriptan and its clinical applications in migraine. Expert Opin Pharmacother. 2002 Jul;3(7):993-1005. Review. PubMed PMID: 12083998.
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17: Lipton RB, Stewart WF. Clinical applications of zolmitriptan (Zomig, 311C90). Cephalalgia. 1997 Oct;17 Suppl 18:53-9. Review. PubMed PMID: 9399017.
18: Rolan P. Potential drug interactions with the novel antimigraine compound zolmitriptan (Zomig, 311C90). Cephalalgia. 1997 Oct;17 Suppl 18:21-7. Review. PubMed PMID: 9399014.
19: Martin GR. Pre-clinical pharmacology of zolmitriptan (Zomig; formerly 311C90), a centrally and peripherally acting 5HT1B/1D agonist for migraine. Cephalalgia. 1997 Oct;17 Suppl 18:4-14. Review. PubMed PMID: 9399012.
20: Mathew N. Zolmitriptan. Introduction. Cephalalgia. 1997 Oct;17 Suppl 18:1-3.  Review. PubMed PMID: 9399011.