MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 598761 | Name: LF 14

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LF 14 affects mammalian non-myelinated nerve fibers.

Chemical Structure

LF 14
LF 14
CAS#88404-01-7

Theoretical Analysis

MedKoo Cat#: 598761

Name: LF 14

CAS#: 88404-01-7

Chemical Formula: C8H12N4O

Exact Mass: 180.1011

Molecular Weight: 180.21

Elemental Analysis: C, 53.32; H, 6.71; N, 31.09; O, 8.88

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
LF 14; LF-14; LF14;
IUPAC/Chemical Name
3-(4-aminopyridin-3-yl)-1,1-dimethylurea
InChi Key
ZGDYCZUBOHHZEE-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H12N4O/c1-12(2)8(13)11-7-5-10-4-3-6(7)9/h3-5H,1-2H3,(H2,9,10)(H,11,13)
SMILES Code
O=C(NC1=C(N)C=CN=C1)N(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
LF 14 affects mammalian non-myelinated nerve fibers.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 180.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: GOODRICH RM, THOMAS RG, WRIGHT SR. A GAMMA RAY DETECTOR OF VARIABLE GEOMETRY FOR WHOLE BODY COUNTING OF SMALL ANIMALS. LF-14. Fission Prod Inhal Proj. 1964 Jul;94:1-15. PubMed PMID: 14273263. 2: Biessels PT, Houwertjes MC, Agoston S, Horn AS. A comparison of the pharmacological actions of 4-aminopyridine and two of its derivatives in the monkey. Eur J Pharmacol. 1987 Mar 17;135(2):155-9. PubMed PMID: 3034626. 3: Den Hertog A, Pielkenrood J, Biessels P, Agoston S. The effect of some new aminopyridines on mammalian non-myelinated nerve fibres. Eur J Pharmacol. 1983 Oct 28;94(3-4):353-5. PubMed PMID: 6653665. 4: Sugimori T, Nagashima H, Vizi ES, Harsing LG Jr, Chaudhry I, Lalezari I, Duncalf D, Goldiner PL, Foldes FF. Effect of mono- and diaminopyridines on release of [3H]norepinephrine from isolated guinea-pig atrium. Neuropharmacology. 1987 Jun;26(6):621-6. PubMed PMID: 3037424. 5: Riesz M, Kápáti E, Szporny L. Antagonism of non-depolarising neuromuscular blockade by aminopyridines in cats. J Pharm Pharmacol. 1986 Feb;38(2):156-8. PubMed PMID: 2870165. 6: Foldes FF, Ludvig N, Nagashima H, Vizi ES. The influence of aminopyridines on Ca2+-dependent evoked release of acetylcholine from rat cortex slices. Neurochem Res. 1988 Aug;13(8):761-4. PubMed PMID: 2845287.