MedKoo Cat#: 563494 | Name: RC-33 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RC-33 HCl is a highly potent, selective, and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.

Chemical Structure

RC-33 HCl
RC-33 HCl
CAS#1346016-43-0

Theoretical Analysis

MedKoo Cat#: 563494

Name: RC-33 HCl

CAS#: 1346016-43-0

Chemical Formula: C21H28ClN

Exact Mass:

Molecular Weight: 329.91

Elemental Analysis: C, 76.45; H, 8.56; Cl, 10.75; N, 4.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
RC-33 Hydrochloride; RC-33 HCl; RC 33 Hydrochloride; RC 33 HCl; RC33 Hydrochloride; RC33 HCl;
IUPAC/Chemical Name
1-(3-([1,1'-biphenyl]-4-yl)butyl)piperidine hydrochloride
InChi Key
IYZBMSKKZQBBKD-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H27N.ClH/c1-18(14-17-22-15-6-3-7-16-22)19-10-12-21(13-11-19)20-8-4-2-5-9-20;/h2,4-5,8-13,18H,3,6-7,14-17H2,1H3;1H
SMILES Code
CC(C1=CC=C(C2=CC=CC=C2)C=C1)CCN3CCCCC3.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 329.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Collina S, Rui M, Stotani S, Bignardi E, Rossi D, Curti D, Giordanetto F, Malacrida A, Scuteri A, Cavaletti G. Are sigma receptor modulators a weapon against multiple sclerosis disease? Future Med Chem. 2017 Nov;9(17):2029-2051. doi: 10.4155/fmc-2017-0122. Epub 2017 Oct 27. PubMed PMID: 29076758. 2: French LB, Lanning CC, Matly M, Harris-Warrick RM. Cellular localization of Shab and Shaw potassium channels in the lobster stomatogastric ganglion. Neuroscience. 2004;123(4):919-30. PubMed PMID: 14751285. 3: Golowasch J, Abbott LF, Marder E. Activity-dependent regulation of potassium currents in an identified neuron of the stomatogastric ganglion of the crab Cancer borealis. J Neurosci. 1999 Oct 15;19(20):RC33. PubMed PMID: 10516335.