Urechistachykinin I | CAS#149097-03-0 | tachykinin-related peptide receptor

MedKoo Cat#: 598679 | Name: Urechistachykinin I

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Urechistachykinin I is a novel tachykinin-related peptide receptor isolated from the echiuroid worm Urechis unicinctus.

Chemical Structure

Urechistachykinin I

CAS#149097-03-0

Theoretical Analysis

MedKoo Cat#: 598679

Name: Urechistachykinin I

CAS#: 149097-03-0

Chemical Formula: C50H85N19O14

Exact Mass: 1175.6523

Molecular Weight: 1176.34

Elemental Analysis: C, 51.05; H, 7.28; N, 22.62; O, 19.04

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Urechistachykinin I; H-Leu-arg-gln-ser-gln-phe-val-gly-ser-arg-NH2;

IUPAC/Chemical Name

(S)-2-((S)-2-((S)-5-amino-2-((S)-2-((S)-2-amino-4-methylpentanamido)-5-guanidinopentanamido)-5-oxopentanamido)-3-hydroxypropanamido)-N1-((6S,9S,15S,18S)-1-amino-6-carbamoyl-9-(hydroxymethyl)-1-imino-15-isopropyl-8,11,14,17-tetraoxo-19-phenyl-2,7,10,13,16-pentaazanonadecan-18-yl)pentanediamide

InChi Key

MXFCWEFJWLZUIJ-RAUUPGJSSA-N

InChi Code

InChI=1S/C50H85N19O14/c1-25(2)20-28(51)41(76)64-30(13-9-19-60-50(57)58)42(77)65-32(15-17-37(53)73)44(79)68-35(24-71)47(82)66-31(14-16-36(52)72)43(78)67-33(21-27-10-6-5-7-11-27)45(80)69-39(26(3)4)48(83)61-22-38(74)62-34(23-70)46(81)63-29(40(54)75)12-8-18-59-49(55)56/h5-7,10-11,25-26,28-35,39,70-71H,8-9,12-24,51H2,1-4H3,(H2,52,72)(H2,53,73)(H2,54,75)(H,61,83)(H,62,74)(H,63,81)(H,64,76)(H,65,77)(H,66,82)(H,67,78)(H,68,79)(H,69,80)(H4,55,56,59)(H4,57,58,60)/t28-,29-,30-,31-,32-,33-,34-,35-,39-/m0/s1

SMILES Code

N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](Cc1ccccc1)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,176.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Sung WS, Lee J, Cho J, Lee DG. The functional role of the tachykinin consensus region of urechistachykinin peptide family for its antimicrobial activity. Biol Pharm Bull. 2011;34(6):921-4. PubMed PMID: 21628896. 2: Ikeda T, Minakata H, Nomoto K, Kubota I, Muneoka Y. Two novel tachykinin-related neuropeptides in the echiuroid worm, Urechis unicinctus. Biochem Biophys Res Commun. 1993 Apr 15;192(1):1-6. PubMed PMID: 8476410. 3: Kawada T, Masuda K, Satake H, Minakata H, Muneoka Y, Nomoto K. Identification of multiple urechistachykinin peptides, gene expression, pharmacological activity, and detection using mass spectrometric analyses. Peptides. 2000 Dec;21(12):1777-83. PubMed PMID: 11150637. 4: Kawada T, Satake H, Minakata H, Muneoka Y, Nomoto K. Characterization of a novel cDNA sequence encoding invertebrate tachykinin-related peptides isolated from the echiuroid worm, Urechis unicinctus. Biochem Biophys Res Commun. 1999 Oct 5;263(3):848-52. PubMed PMID: 10512769. 5: Sung WS, Park SH, Lee DG. Antimicrobial effect and membrane-active mechanism of Urechistachykinins, neuropeptides derived from Urechis unicinctus. FEBS Lett. 2008 Jul 9;582(16):2463-6. doi: 10.1016/j.febslet.2008.06.015. Epub 2008 Jun 18. PubMed PMID: 18570895. 6: Ikeda T, Minakata H, Nomoto K. The importance of C-terminal residues of vertebrate and invertebrate tachykinins for their contractile activities in gut tissues. FEBS Lett. 1999 Nov 19;461(3):201-4. PubMed PMID: 10567697.