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MedKoo Cat#: 598657 | Name: Leucomycin A1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Leucomycin A1 is a major and potent metabolite from the leucomycin complex.

Chemical Structure

Leucomycin A1
Leucomycin A1
CAS#16846-34-7

Theoretical Analysis

MedKoo Cat#: 598657

Name: Leucomycin A1

CAS#: 16846-34-7

Chemical Formula: C40H67NO14

Exact Mass: 785.4562

Molecular Weight: 785.96

Elemental Analysis: C, 61.13; H, 8.59; N, 1.78; O, 28.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Leucomycin A1; Kitasamycin A1; LM-A1; Leucomycin V 4-isovalerate; Turimycin H5;
IUPAC/Chemical Name
(2S,3S,4R,6S)-6-(((2R,3S,4R,5R,6S)-6-(((4R,5S,6S,7R,9R,10R,11E,13Z,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl)oxy)-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 3-methylbutanoate
InChi Key
IEMDOFXTVAPVLX-BRSNCBHMSA-N
InChi Code
InChI=1S/C40H67NO14/c1-22(2)18-30(45)53-38-26(6)51-32(21-40(38,7)48)54-35-25(5)52-39(34(47)33(35)41(8)9)55-36-27(16-17-42)19-23(3)28(43)15-13-11-12-14-24(4)50-31(46)20-29(44)37(36)49-10/h11-13,15,17,22-29,32-39,43-44,47-48H,14,16,18-21H2,1-10H3/b12-11-,15-13+/t23-,24-,25-,26+,27+,28+,29-,32+,33-,34-,35-,36+,37+,38+,39+,40-/m1/s1
SMILES Code
C[C@@H](O[C@@H](O[C@@H]1[C@@H](OC)[C@H](O)CC(O[C@H](C)C/C=C\C=C\[C@H](O)[C@H](C)C[C@@H]1CC=O)=O)[C@H](O)[C@H]2N(C)C)[C@H]2O[C@H]3C[C@@](C)(O)[C@H]([C@H](C)O3)OC(CC(C)C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 785.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hoshino Y, Matsumae A, Yamamoto H, Hata T. Studies on leucomycin A1. I. Biological studies. J Antibiot (Tokyo). 1966 Jan;19(1):23-9. PubMed PMID: 5952018. 2: Hoshino Y, Matsumae A, Yamamoto H, Hata T. Studies on leucomycin A1. IV. Combined effects with sulfa drugs. J Antibiot (Tokyo). 1966 Jan;19(1):42-8. PubMed PMID: 5952021. 3: Hu M, Hu CQ. [Identification of the components and products of hydrolysis in acetylleucomycin by LC-MS]. Yao Xue Xue Bao. 2006 May;41(5):476-80. Chinese. PubMed PMID: 16848328. 4: Hoshino Y, Umezawa I, Yoshida T, Matsumae A, Yamamoto H, Hata T. Studies on leucomycin A1. 3. Experimental treatments of animal infected with several pathogene bacteria. J Antibiot (Tokyo). 1966 Jan;19(1):37-41. PubMed PMID: 5952020. 5: Hoshino Y, Umezawa I, Yamamoto H, Matsumae A, Hata T. Studies on leucomycin A1. II. Studies on blood and tissue levels, and toxicities. J Antibiot (Tokyo). 1966 Jan;19(1):30-6. PubMed PMID: 5952019.