Letimide HCl | CAS#21791-39-9 | Analgesic

MedKoo Cat#: 598619 | Name: Letimide HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Letimide HCl is an analgesic.

Chemical Structure

Letimide HCl

CAS#21791-39-9 (HCl)

Theoretical Analysis

MedKoo Cat#: 598619

Name: Letimide HCl

CAS#: 21791-39-9 (HCl)

Chemical Formula: C14H19ClN2O3

Exact Mass: 0.0000

Molecular Weight: 298.76

Elemental Analysis: C, 56.28; H, 6.41; Cl, 11.87; N, 9.38; O, 16.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

26513-90-6 (free base) 21791-39-9 (HCl)

Synonym

Letimide hydrochloride; Letimide HCl; MA-1443; MA 1443; MA1443;

IUPAC/Chemical Name

3-(2-(diethylamino)ethyl)-2H-benzo[e][1,3]oxazine-2,4(3H)-dione hydrochloride

InChi Key

QPFDPUCWRFYCFB-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H18N2O3.ClH/c1-3-15(4-2)9-10-16-13(17)11-7-5-6-8-12(11)19-14(16)18;/h5-8H,3-4,9-10H2,1-2H3;1H

SMILES Code

O=C(N1CCN(CC)CC)OC2=CC=CC=C2C1=O.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 298.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Díaz Barriga-Arceo S, Madrigal-Bujaidar E, Salazar M, Chamorro G. Cytogenetic and teratogenic evaluation of letimide. Toxicol Lett. 1991 Apr;56(1-2):99-107. PubMed PMID: 2017790. 2: Díaz Barriga-Arceo S, Madrigal-Bujaidar E. Genotoxic evaluation of letimide with the mouse bone marrow micronucleus test. Toxicol Lett. 1991 Apr;56(1-2):95-8. PubMed PMID: 2017789. 3: Etienne MC, Oster W, Milano G. Development and validation of a chiral high-performance liquid chromatography assay for rogletimide and rogletimide-N-oxide isomers in plasma. Cancer Chemother Pharmacol. 1996;38(4):343-8. PubMed PMID: 8674157.