Demecolcine Hydrobromide Salt is an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Demecolceine induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
MedKoo Cat#: 574654
Name: Demecolcine Hydrobromide
CAS#: 1246817-95-7 (HBr)
Chemical Formula: C21H26BrNO5
Exact Mass: 451.0994
Molecular Weight: 452.34
Elemental Analysis: C, 55.76; H, 5.79; Br, 17.66; N, 3.10; O, 17.68
The following data is based on the product molecular weight 452.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
