Danicopan, aslo known as ACH-4471 and ACH-0144471, is a highly potent, orally active Factor D inhibitor. Danicopan selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.
MedKoo Cat#: 563457
Name: Danicopan HCl
CAS#: Danicopan HCl
Chemical Formula: C26H24BrClFN7O3
Exact Mass: 579.1030
Molecular Weight: 616.88
Elemental Analysis: C, 50.62; H, 3.92; Br, 12.95; Cl, 5.75; F, 3.08; N, 15.89; O, 7.78
The following data is based on the product molecular weight 616.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
