Pipratecol | CAS# 15534-05-1 | H+/K(+)-ATPase inhibitor

MedKoo Cat#: 592588 | Name: Pipratecol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pipratecol is substituted thienoimidazole. It is the H+/K(+)-ATPase inhibitor.

Chemical Structure

Pipratecol

CAS#15534-05-1 (free base)

Theoretical Analysis

MedKoo Cat#: 592588

Name: Pipratecol

CAS#: 15534-05-1 (free base)

Chemical Formula: C19H24N2O4

Exact Mass: 344.1736

Molecular Weight: 344.41

Elemental Analysis: C, 66.26; H, 7.02; N, 8.13; O, 18.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

15622-04-5 (2HCl) 15534-05-1 (free base)

Synonym

Pipratecol

IUPAC/Chemical Name

alpha-(3,4-Dihydroxyphenyl)-4-(2-methoxyphenyl)-1-piperazineethanol

InChi Key

QESTYTNSJJTQCI-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H24N2O4/c1-25-19-5-3-2-4-15(19)21-10-8-20(9-11-21)13-18(24)14-6-7-16(22)17(23)12-14/h2-7,12,18,22-24H,8-11,13H2,1H3

SMILES Code

OC(C1=CC=C(O)C(O)=C1)CN2CCN(C3=CC=CC=C3OC)CC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 344.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Cattaneo M, D'Angelo A, Mannucci PM, Pareti F, Vanasia S, Viganò. [Effect of raubasine and pipratecol on platelet aggregation and on the platelet release reaction]. Clin Ter. 1980 Feb 29;92(4):359-68. Italian. PubMed PMID: 6108818. 2: Passero S, Battistini N. Effect of a Raubasine-Pipratecol association (Isosarpan) on the sympathetic control of cerebral circulation. Acta Neurol (Napoli). 1979 Feb;1(1):45-58. PubMed PMID: 433680. 3: Laubie M, Le Douarec JC. [Pharmacological study of pipratecol (JP 711) and of a pharmaceutical combination raubasine-JP 711]. Arzneimittelforschung. 1969 Nov;19(11):1820-6. French. PubMed PMID: 4391788. 4: Beil W, Staar U, Sewing KF. Substituted thieno[3,4-d]imidazoles, a novel group of H+/K(+)-ATPase inhibitors. Differentiation of their inhibition characteristics from those of omeprazole. Eur J Pharmacol. 1990 Oct 23;187(3):455-67. PubMed PMID: 1963594.