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MedKoo Cat#: 341121 | Name: Yau 17
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Yau 17 (cis-1-benzoyloxy-2-dimethylamino-1,2,3,4-tetrahydronaphthalene) is a chiral compound studied for its local anesthetic and neuroactive properties. It likely works by modulating neurotransmitter systems, such as serotonin or dopamine, and could act as a monoamine transporter or GPCR modulator. Current research suggests potential applications in anesthesia and possibly in treating mood disorders or cognitive functions

Chemical Structure

Yau 17
Yau 17
CAS#60036-90-0

Theoretical Analysis

MedKoo Cat#: 341121

Name: Yau 17

CAS#: 60036-90-0

Chemical Formula: C19H21NO2

Exact Mass: 295.1572

Molecular Weight: 295.38

Elemental Analysis: C, 77.26; H, 7.17; N, 4.74; O, 10.83

Price and Availability

Size Price Availability Quantity
25mg USD 350.00
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Related CAS #
No Data
Synonym
Yau 17; Yau-17; Yau17.
IUPAC/Chemical Name
1-Naphthalenol, 2-(dimethylamino)-1,2,3,4-tetrahydro-, benzoate (ester), cis-(+-)-
InChi Key
LBQGJHNNGUZLOH-ZWKOTPCHSA-N
InChi Code
InChI=1S/C19H21NO2/c1-20(2)17-13-12-14-8-6-7-11-16(14)18(17)22-19(21)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3/t17-,18+/m0/s1
SMILES Code
CN(C)[C@H]1CCc2ccccc2[C@H]1OC(=O)c3ccccc3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 295.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Inclusion of fluorophores in cyclodextrins: a closer look at the fluorometric determination of association constants by linear and nonlinear fitting procedures. Methods Appl Fluoresc. 2017 Dec 13;6(1):013001. doi: 10.1088/2050-6120/aa8d96. PubMed PMID: 28925371. 11: Lee HS. Recent advances in topical anesthesia. J Dent Anesth Pain Med. 2016 Dec;16(4):237-244. doi: 10.17245/jdapm.2016.16.4.237. Epub 2016 Dec 31. Review. PubMed PMID: 28879311; PubMed Central PMCID: PMC5564188. 12: Vohra R, Huntington S, Koike J, Le K, Geller RJ. Pediatric Exposures to Topical Benzocaine Preparations Reported to a Statewide Poison Control System. West J Emerg Med. 2017 Aug;18(5):923-927. doi: 10.5811/westjem.2017.6.33665. Epub 2017 Jul 14. PubMed PMID: 28874945; PubMed Central PMCID: PMC5576629. 13: Patel MA, AbouGhaly MHH, Chadwick K. The discovery and investigation of a crystalline solid solution of an active pharmaceutical ingredient. Int J Pharm. 2017 Oct 30;532(1):166-176. doi: 10.1016/j.ijpharm.2017.08.101. Epub 2017 Aug 25. PubMed PMID: 28847668. 14: Mohamed MA, Atty SA, Merey HA, Fattah TA, Foster CW, Banks CE. Titanium nanoparticles (TiO(2))/graphene oxide nanosheets (GO): an electrochemical sensing platform for the sensitive and simultaneous determination of benzocaine in the presence of antipyrine. Analyst. 2017 Oct 7;142(19):3674-3679. doi: 10.1039/c7an01101f. Epub 2017 Aug 24. PubMed PMID: 28836639. 15: Nahon S, Séité S, Kolasinski J, Aguirre P, Geurden I. Effects of euthanasia methods on stable carbon (δ(13) C value) and nitrogen (δ(15) N value) isotopic compositions of fry and juvenile rainbow trout Oncorhynchus mykiss. Rapid Commun Mass Spectrom. 2017 Oct 30;31(20):1742-1748. doi: 10.1002/rcm.7958. PubMed PMID: 28805256. 16: Sewell CR, Rivey MP. A Case Report of Benzocaine-Induced Methemoglobinemia. J Pharm Pract. 2017 Jan 1:897190017723211. doi: 10.1177/0897190017723211. [Epub ahead of print] PubMed PMID: 28803519. 17: Readman GD, Owen SF, Knowles TG, Murrell JC. Species specific anaesthetics for fish anaesthesia and euthanasia. Sci Rep. 2017 Aug 2;7(1):7102. doi: 10.1038/s41598-017-06917-2. PubMed PMID: 28769117; PubMed Central PMCID: PMC5541135. 18: Stringhetta GR, Barbas LAL, Maltez LC, Sampaio LA, Monserrat JM, Garcia LO. Oxidative stress responses of juvenile tambaqui Colossoma macropomum after short-term anesthesia with benzocaine and MS-222. An Acad Bras Cienc. 2017;89(3 Suppl):2209-2218. doi: 10.1590/0001-3765201720160823. Epub 2017 Jul 24. PubMed PMID: 28746612. 19: Chintala K, Kumar SP, Murthy KRV. Comparative evaluation of effectiveness of intra-pocket anesthetic gel and injected local anesthesia during scaling and root planing - A split-mouth clinical trial. Indian J Dent Res. 2017 May-Jun;28(3):281-285. doi: 10.4103/ijdr.IJDR_489_16. PubMed PMID: 28721992. 20: Skår MW, Haugland GT, Powell MD, Wergeland HI, Samuelsen OB. 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CL-387785

CL-387785

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