Butaperazine maleate | CAS#1063-55-4 | antipsychotic

MedKoo Cat#: 461221 | Name: Butaperazine maleate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Butaperazine maleate is a phenothiazine derivative and antipsychotic agent.

Chemical Structure

Butaperazine maleate

CAS#1063-55-4 (maleate)

Theoretical Analysis

MedKoo Cat#: 461221

Name: Butaperazine maleate

CAS#: 1063-55-4 (maleate)

Chemical Formula: C32H39N3O9S

Exact Mass: 641.2407

Molecular Weight: 641.73

Elemental Analysis: C, 59.89; H, 6.13; N, 6.55; O, 22.44; S, 5.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

653-03-2 (free base) 1063-55-4 (maleate)

Synonym

Butaperazine maleate; Repoise maleate; Tyrylen;

IUPAC/Chemical Name

1-(10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazin-2-yl)butan-1-one dimaleate

InChi Key

WVYWSPZQGQMPKW-SPIKMXEPSA-N

InChi Code

InChI=1S/C24H31N3OS.2C4H4O4/c1-3-7-22(28)19-10-11-24-21(18-19)27(20-8-4-5-9-23(20)29-24)13-6-12-26-16-14-25(2)15-17-26;2*5-3(6)1-2-4(7)8/h4-5,8-11,18H,3,6-7,12-17H2,1-2H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

SMILES Code

CCCC(C(C=C1N2CCCN3CCN(C)CC3)=CC=C1SC4=C2C=CC=C4)=O.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 641.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Evaluation of a new antipsychotic agent. Butaperazine maleate (repoise maleate). JAMA. 1968 Dec 2;206(10):2307-8. PubMed PMID: 4386884. 2: Robins AH. Butaperazine maleate (Repoise maleate). Clin Pharmacol Ther. 1969 May-Jun;10(3):428-30. PubMed PMID: 4389667. 3: Kala H, Wendorff D, Moldenhauer H. [Studies on the solubility and the distribution behaviour of butaperazine dihydrogen maleate (author's transl)]. Pharmazie. 1980;34(5-6):306-10. German. PubMed PMID: 6106207. 4: el-Yousef MK, Manier DH. Letter: The effect of benztropine mesylate on plasma levels of butaperazine maleate. Am J Psychiatry. 1974 Apr;131(4):471-2. PubMed PMID: 4149998. 5: Casper R, Garver DL, Dekirmenjian H, Chang S, Davis JM. Phenothiazine levels in plasma and red blood cells. Their relationship to clinical improvement in schizophrenia. Arch Gen Psychiatry. 1980 Mar;37(3):301-5. PubMed PMID: 6102458. 6: Gowda HS, Ahmed SA. N-substituted phenothiazines as redox indicators in bromatometry. Talanta. 1979 Mar;26(3):233-5. PubMed PMID: 18962421.