MedKoo Cat#: 592516 | Name: Alentemol free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Alentemol (U-66444B) is a selective dopamine agonist acting at presynaptic receptors to inhibit the release of dopamine. In preclinical studies the compound caused hypothermia in mice and inhibited amphetamine-stimulated omtor activity in mice.

Chemical Structure

Alentemol free base
Alentemol free base
CAS#112891-97-1 (free base)

Theoretical Analysis

MedKoo Cat#: 592516

Name: Alentemol free base

CAS#: 112891-97-1 (free base)

Chemical Formula: C19H25NO

Exact Mass: 283.1936

Molecular Weight: 283.42

Elemental Analysis: C, 80.52; H, 8.89; N, 4.94; O, 5.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
Synonym
Alentemol free base; Alentemol, alentamol, U-66444B; U 66444B; U66444B;
IUPAC/Chemical Name
1H-Phenalen-5-ol, 2,3-dihydro-2-(dipropylamino)-
InChi Key
TWUJBHBRYYTEDL-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H25NO/c1-3-8-20(9-4-2)17-10-14-6-5-7-15-12-18(21)13-16(11-17)19(14)15/h5-7,12-13,17,21H,3-4,8-11H2,1-2H3
SMILES Code
OC1=CC2=C3C(CC(N(CCC)CCC)C2)=CC=CC3=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 283.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yu RL, Aaron CS, Ulrich RG, Thilagar A, Kumaroo PV, Wang Y. Chromosomal breakage following treatment of CHO-K1 cells in vitro with U-68,553B is due to induction of undercondensation of heterochromatin. Environ Mol Mutagen. 1992;20(3):172-87. doi: 10.1002/em.2850200306. PMID: 1396608. 2: Althaus JS, Decker DE, Von Voigtlander PF, Buxser SE. Effects of dopamine agonists on dopamine secretion from PC12 cells: lack of functional autoreceptor activity. Res Commun Chem Pathol Pharmacol. 1991 May;72(2):131-42. PMID: 1678897. 3: Schwende FJ, Rykert UM. Determination of alentamol hydrobromide, a novel antipsychotic agent, in human blood plasma and urine by high-performance liquid chromatography with fluorescence detection and solid-phase extraction. J Chromatogr. 1991 Apr 19;565(1-2):488-96. doi: 10.1016/0378-4347(91)80415-9. PMID: 1874898. 4: Piercey MF, Broderick PA, Hoffmann WE, Vogelsang GD. U-66444B and U-68553B, potent autoreceptor agonists at dopaminergic cell bodies and terminals. J Pharmacol Exp Ther. 1990 Aug;254(2):369-74. PMID: 1974631.