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MedKoo Cat#: 592512 | Name: Eprozinol dihydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Eprozinol dihydrochloride has anti-bronchoconstrictive effect.

Chemical Structure

Eprozinol dihydrochloride
Eprozinol dihydrochloride
CAS# 27588-43-8 (2HCl)

Theoretical Analysis

MedKoo Cat#: 592512

Name: Eprozinol dihydrochloride

CAS#: 27588-43-8 (2HCl)

Chemical Formula: C22H32Cl2N2O2

Exact Mass: 426.1841

Molecular Weight: 427.41

Elemental Analysis: C, 61.82; H, 7.55; Cl, 16.59; N, 6.55; O, 7.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
27588-43-8 (2HCl) 32665-36-4 (free base)
Synonym
Eprozinol dihydrochloride
IUPAC/Chemical Name
1-Piperazinepropanol, 4-(beta-methoxyphenethyl)-alpha-phenyl-, dihydrochloride
InChi Key
KVKUGOLSESPAPP-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H30N2O2.2ClH/c1-26-22(20-10-6-3-7-11-20)18-24-16-14-23(15-17-24)13-12-21(25)19-8-4-2-5-9-19;;/h2-11,21-22,25H,12-18H2,1H3;2*1H
SMILES Code
OC(C1=CC=CC=C1)CCN2CCN(CC(OC)C3=CC=CC=C3)CC2.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 427.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Merigot P, Garnier R, Efthymiou ML. [Convulsions with 3 antitussive substituted derivatives of piperazine (zipeprol, eprazinone, eprozinol)]. Ann Pediatr (Paris). 1985 Jun;32(6):504-6, 511. French. PubMed PMID: 4026148. 2: Labrid C, Duchene-Marullaz P, Rispat G. Mechanisms of anti-bronchoconstrictive effects of eprozinol. II. In vivo studies on the guinea pig. Pharmacology. 1981;23(1):48-55. PubMed PMID: 7312935. 3: Labrid C, Burtin C, Stoclet JC, Dureng G, Schoeffter P, Lebel B, Duchene-Marullaz P. Mechanisms of anti-bronchoconstrictive effects of eprozinol. I. In vitro studies. Pharmacology. 1981;23(1):31-47. PubMed PMID: 6171839. 4: Nicrosini F, Carpinella G. [Eprozinol treatment of chronic bronchitis with dyspnea and cough]. Bronchopneumologie. 1978 Jul-Aug;28(4):322-7. French. PubMed PMID: 756799. 5: Labrid C, Dureng G, Duchene-Marullaz P, Moleyre J. Dualist or pseudo-dualist interactions of mepyramine, diphenhydramine and eprozinol with histamine at H1-receptors. Jpn J Pharmacol. 1977 Aug;27(4):491-500. PubMed PMID: 21982. 6: Duchene-Marullaz P, Rispat G, Perriere JP. [Several antihistaminic pharmacodynamic aspects, especially of Eprozinol]. Therapie. 1971 Jan-Feb;26(1):155-62. French. PubMed PMID: 4396627.