RO5353 is a potent and orally active p53-MDM2 inhibitor. The development of small-molecule MDM2 inhibitors to restore dysfunctional p53 activities represents a novel approach for cancer treatment.
MedKoo Cat#: 561882
Name: RO5353
CAS#: 1360821-61-9
Chemical Formula: C29H29Cl2FN4O4S
Exact Mass: 618.1271
Molecular Weight: 619.53
Elemental Analysis: C, 56.22; H, 4.72; Cl, 11.44; F, 3.07; N, 9.04; O, 10.33; S, 5.17
The following data is based on the product molecular weight 619.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
