Lankacyclinol A | CAS#52212-91-6 | Lankacidin Antibiotic

MedKoo Cat#: 559160 | Name: Lankacyclinol A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lankacyclinol A is a Lankacidin Antibiotic.

Chemical Structure

Lankacyclinol A

CAS#52212-91-6

Theoretical Analysis

MedKoo Cat#: 559160

Name: Lankacyclinol A

CAS#: 52212-91-6

Chemical Formula: C26H37NO6

Exact Mass: 459.2621

Molecular Weight: 459.58

Elemental Analysis: C, 67.95; H, 8.12; N, 3.05; O, 20.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Lankacyclinol A; Antibiotic T 2636 E; T-2636-E; T 2636-E; T2636-E;

IUPAC/Chemical Name

(2E,4E,8E,10E,15E)-7-hydroxy-12-(2-hydroxypropanamido)-4,10,13,15-tetramethyl-14-oxocycloheptadeca-2,4,8,10,15-pentaen-1-yl acetate

InChi Key

CHSNOFZXJPAESZ-KCJBODNSSA-N

InChi Code

InChI=1S/C26H37NO6/c1-16-7-11-22(30)12-8-17(2)15-24(27-26(32)20(5)28)19(4)25(31)18(3)10-14-23(13-9-16)33-21(6)29/h7-10,12-13,15,19-20,22-24,28,30H,11,14H2,1-6H3,(H,27,32)/b12-8+,13-9+,16-7+,17-15+,18-10+

SMILES Code

CC(O)C(NC1/C=C(C)/C=C/C(O)C/C=C(C)/C=C/C(OC(C)=O)C/C=C(C)/C(C1C)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 459.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Williams DR, Cortez GS, Bogen SL, Rojas CM. Total Synthesis of Lankacyclinol Generous financial support for this research was provided by the National Institutes of Health (Award no.: GM41560). Additionally, a National Institutes of Health Minority Predoctoral Fellowship (Award no.: GM18547) to G.S.C. is gratefully acknowledged. We also wish to thank Dr. Tsuneaki Hida and Dr. Yoshio Kozai, Takeda Chemical Ltd. (Japan), for providing us with an authentic sample of lankacyclinol as well as copies of the original (1)H NMR spectrum. . Angew Chem Int Ed Engl. 2000 Dec 15;39(24):4612-4615. PubMed PMID: 11169688. 2: Zheng K, Shen D, Hong R. Biomimetic Synthesis of Lankacidin Antibiotics. J Am Chem Soc. 2017 Sep 20;139(37):12939-12942. doi: 10.1021/jacs.7b08500. Epub 2017 Sep 6. PubMed PMID: 28853876.