IUPAC/Chemical Name
3-((2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)carbamoyl)pyridine 1-oxide
InChi Key
HIVRCMFJEMKPDS-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H21N3O3S/c1-18(2)11-14-5-6-15(22-14)12-23-9-7-17-16(20)13-4-3-8-19(21)10-13/h3-6,8,10H,7,9,11-12H2,1-2H3,(H,17,20)
SMILES Code
CN(C)Cc1oc(CSCCNC(c(ccc2)cn2=O)=O)cc1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
335.42
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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6: Wilson JA, Johnston D, Penston J, Wormsley KG. Gastric inhibitory effects of CM57755. A new histamine H2 receptor antagonist. Eur J Clin Pharmacol. 1986;30(1):33-6. PubMed PMID: 2872060.
7: Necciari J, Mery D, Garriot P, Escourrou J, Cautreels W. Pharmacokinetics of CM 57755, a new histamine H2-receptor antagonist, after single oral doses in man. Int J Clin Pharmacol Res. 1985;5(6):457-65. PubMed PMID: 2869002.
8: Lavezzo A, Manzoni L, Aureggi G, Nisato D, Bianchetti A, Carminati P. In vivo and in vitro effects of CM 57755, a new gastric antisecretory agent acting on histamine H2 receptors. Int J Tissue React. 1984;6(2):155-65. PubMed PMID: 6145676.
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