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MedKoo Cat#: 592135 | Name: Palmitone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Palmitone prevents pentylenetetrazole-caused neuronal damage in the CA3 hippocampal region.

Chemical Structure

Palmitone
Palmitone
CAS#502-73-8

Theoretical Analysis

MedKoo Cat#: 592135

Name: Palmitone

CAS#: 502-73-8

Chemical Formula: C31H62O

Exact Mass: 450.4801

Molecular Weight: 450.84

Elemental Analysis: C, 82.59; H, 13.86; O, 3.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Palmitone; NSC 953; NSC-953; NSC953
IUPAC/Chemical Name
16-Hentriacontanone
InChi Key
UNRFDARCMOHDBJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C31H62O/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31(32)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-30H2,1-2H3
SMILES Code
CCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 450.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pereira MDP, da Silva T, Aguiar ACC, Oliva G, Guido RVC, Yokoyama-Yasunaka JKU, Uliana SRB, Lopes LMX. Chemical Composition, Antiprotozoal and Cytotoxic Activities of Indole Alkaloids and Benzofuran Neolignan of Aristolochia cordigera. Planta Med. 2017 Jul;83(11):912-920. doi: 10.1055/s-0043-104776. Epub 2017 Mar 6. PubMed PMID: 28264205. 2: Cano-Europa E, González-Trujano ME, Reyes-Ramírez A, Hernández-García A, Blas-Valdivia V, Ortiz-Butrón R. Palmitone prevents pentylenetetrazole-caused neuronal damage in the CA3 hippocampal region of prepubertal rats. Neurosci Lett. 2010 Feb 12;470(2):111-4. doi: 10.1016/j.neulet.2009.12.066. Epub 2009 Dec 31. PubMed PMID: 20045039. 3: Carballo AI, Martínez AL, González-Trujano ME, Pellicer F, Ventura-Martínez R, Díaz-Reval MI, López-Muñoz FJ. Antinociceptive activity of Annona diversifolia Saff. leaf extracts and palmitone as a bioactive compound. Pharmacol Biochem Behav. 2010 Mar;95(1):6-12. doi: 10.1016/j.pbb.2009.11.017. Epub 2009 Dec 5. PubMed PMID: 19969018. 4: González-Trujano ME, López-Meraz L, Reyes-Ramírez A, Aguillón M, Martínez A. Effect of repeated administration of Annona diversifolia Saff. (ilama) extracts and palmitone on rat amygdala kindling. Epilepsy Behav. 2009 Dec;16(4):590-5. doi: 10.1016/j.yebeh.2009.09.018. PubMed PMID: 19836312. 5: Shanker KS, Kanjilal S, Rao BV, Kishore KH, Misra S, Prasad RB. Isolation and antimicrobial evaluation of isomeric hydroxy ketones in leaf cuticular waxes of Annona squamosa. Phytochem Anal. 2007 Jan-Feb;18(1):7-12. PubMed PMID: 17260693. 6: Eva González-Trujano M, Tapia E, López-Meraz L, Navarrete A, Reyes-Ramírez A, Martínez A. Anticonvulsant effect of Annona diversifolia Saff. and palmitone on penicillin-induced convulsive activity. A behavioral and EEG study in rats. Epilepsia. 2006 Nov;47(11):1810-7. PubMed PMID: 17116019. 7: González-Trujano ME, Martínez AL, Reyes-Ramírez A, Reyes-Trejo B, Navarrete A. Palmitone isolated from Annona diversifolia induces an anxiolytic-like effect in mice. Planta Med. 2006 Jun;72(8):703-7. Epub 2006 May 29. PubMed PMID: 16732521. 8: López-Rubalcava C, Piña-Medina B, Estrada-Reyes R, Heinze G, Martínez-Vázquez M. Anxiolytic-like actions of the hexane extract from leaves of Annona cherimolia in two anxiety paradigms: possible involvement of the GABA/benzodiazepine receptor complex. Life Sci. 2006 Jan 11;78(7):730-7. Epub 2005 Aug 24. PubMed PMID: 16122763. 9: Estrada-Reyes R, Alvarez AL, López-Rubalcava C, Rocha L, Heinze G, Moreno J, Martínez-Vázquez M. Lignans from leaves of Rollinia mucosa. Z Naturforsch C. 2002 Jan-Feb;57(1-2):29-32. PubMed PMID: 11926539. 10: González-Trujano ME, Navarrete A, Reyes B, Cedillo-Portugal E, Hong E. Anticonvulsant properties and bio-guided isolation of palmitone from leaves of Annona diversifolia. Planta Med. 2001 Mar;67(2):136-41. PubMed PMID: 11301859. 11: Ahibo-Coffy A, Aurelle H, Lacave C, Prome JC, Puzo G, Savagnac A. Isolation, structural studies and chemical synthesis of a 'palmitone lipid' from Corynebacterium diphtheriae. Chem Phys Lipids. 1978 Oct;22(3):185-95. PubMed PMID: 102431.

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