Synonym
2-Acetylfluorene; 2 Acetylfluorene; 2Acetylfluorene; 2-Fluorenyl methyl ketone; 2-Acetofluorene;
IUPAC/Chemical Name
Ethanone, 1-(9H-fluoren-2-yl)- (9CI)
InChi Key
IBASEVZORZFIIH-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H12O/c1-10(16)11-6-7-15-13(8-11)9-12-4-2-3-5-14(12)15/h2-8H,9H2,1H3
SMILES Code
CC(C1=CC(CC2=C3C=CC=C2)=C3C=C1)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
208.26
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: SARGENT LJ, SMALL L. Amino carbinols derived from 2-acetylfluorene. J Org Chem. 1948 Jul;13(4):608-12. PubMed PMID: 18873341.
2: Zawirska B, Medraś K, Sośnik H. [Pyrrole pigments of organs during 2-amino-N-acetylfluorene-induced carcinogenesis in rats]. Zentralbl Allg Pathol. 1971;114(1):41-50. German. PubMed PMID: 4325442.
3: Sugasawa K, Masutani C, Uchida A, Maekawa T, van der Spek PJ, Bootsma D, Hoeijmakers JH, Hanaoka F. HHR23B, a human Rad23 homolog, stimulates XPC protein in nucleotide excision repair in vitro. Mol Cell Biol. 1996 Sep;16(9):4852-61. PubMed PMID: 8756644; PubMed Central PMCID: PMC231487.
4: Robinson PD, Lutfi HG, Hou Y, Meyers CY. 1,1-Di(9-fluorenyl)ethyl acetate, a by-product from the acetylation of 9-fluorenyllithium. Acta Crystallogr C. 2001 May;57(Pt 5):582-4. Epub 2001 May 15. PubMed PMID: 11353259.
5: Robinson PD, Lutfi HG, Hou Y, Meyers CY. 9-(1-Acetoxyethylidene)fluorene ("diacetylfluorene"), a by-product from the acetylation of 9-fluorenyllithium. Acta Crystallogr C. 2001 Apr;57(Pt 4):428-30. PubMed PMID: 11313583.
