MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 461079 | Name: Irtemazole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Irtemazole is a uricosuric substance.

Chemical Structure

Irtemazole
Irtemazole
CAS#115574-30-6

Theoretical Analysis

MedKoo Cat#: 461079

Name: Irtemazole

CAS#: 115574-30-6

Chemical Formula: C18H16N4

Exact Mass: 288.1375

Molecular Weight: 288.35

Elemental Analysis: C, 74.98; H, 5.59; N, 19.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Irtemazole; R 60844; R-60844; R60844;
IUPAC/Chemical Name
5-((1H-imidazol-1-yl)(phenyl)methyl)-2-methyl-1H-benzo[d]imidazole
InChi Key
DCGOMTSIZLGUOK-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H16N4/c1-13-20-16-8-7-15(11-17(16)21-13)18(22-10-9-19-12-22)14-5-3-2-4-6-14/h2-12,18H,1H3,(H,20,21)
SMILES Code
CC1=NC2=CC(C(N3C=CN=C3)C4=CC=CC=C4)=CC=C2N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 288.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gresser U, Kamilli I, Kronawitter U, Zöllner N. Uricosuric effect of different doses of irtemazole in normouricaemic subjects. Eur J Clin Pharmacol. 1990;38(5):489-91. PubMed PMID: 2379534. 2: Kamilli I, Gresser U, Zöllner N. Pharmacokinetics and pharmacodynamics of different doses of Irtemazole in repeated application. Z Rheumatol. 1991 Jan-Feb;50(1):23-8. PubMed PMID: 1905451. 3: Gresser U, Zöllner N. Uricosuric effect of irtemazole in healthy subjects. Klin Wochenschr. 1989 Oct 2;67(19):971-5. PubMed PMID: 2615290. 4: Kamilli I, Gresser U, Pellkofer T, Löffler W, Zöllner N. Uricosuric effect of irtemazole in hyperuricemic patients without and with renal insufficiency. Z Rheumatol. 1989 Nov-Dec;48(6):307-12. PubMed PMID: 2623976. 5: Gresser U, Kronawitter U, Adjan O, Zöllner N. Rapid onset of uricosuria after oral administration of irtemazole, an uricosuric substance. Klin Wochenschr. 1989 Oct 17;67(20):1058-60. PubMed PMID: 2586012. 6: Gresser U, Zöllner N. A new uricosuric substance 5-[(1H-imidazol-1-yl)phenylmethyl]-2-methyl-1H-benzimidazole (C18H16N4). Klin Wochenschr. 1989 Jun 15;67(12):645. PubMed PMID: 2770180. 7: Gresser U. [Uric acid level in blood donors of southern Germany--almost constant since 1971]. Fortschr Med. 1991 Jul 30;109(22):449. German. PubMed PMID: 1937325.