Synonym
Gentiakochianin; BRN 1351024; BRN-1351024; BRN1351024; NSC 289490.
IUPAC/Chemical Name
Xanthen-9-one, 6-methoxy-1,2,8-trihydroxy-
InChi Key
BDBVOZGRVBXANN-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H10O6/c1-19-6-4-8(16)11-10(5-6)20-9-3-2-7(15)13(17)12(9)14(11)18/h2-5,15-17H,1H3
SMILES Code
O=C1C2=C(OC3=C1C(O)=CC(OC)=C3)C=CC(O)=C2O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
274.23
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Isakovic A, Jankovic T, Harhaji L, Kostic-Rajacic S, Nikolic Z, Vajs V, Trajkovic V. Antiglioma action of xanthones from Gentiana kochiana: Mechanistic and structure-activity requirements. Bioorg Med Chem. 2008 May 15;16(10):5683-94. doi: 10.1016/j.bmc.2008.03.069. Epub 2008 Mar 30. PubMed PMID: 18406151.
2: Tomić M, Tovilović G, Butorović B, Krstić D, Janković T, Aljancić I, Menković N. Neuropharmacological evaluation of diethylether extract and xanthones of Gentiana kochiana. Pharmacol Biochem Behav. 2005 Jul;81(3):535-42. PubMed PMID: 15932769.
3: Chericoni S, Testai L, Calderone V, Flamini G, Nieri P, Morelli I, Martinotti E. The xanthones gentiacaulein and gentiakochianin are responsible for the vasodilator action of the roots of Gentiana kochiana. Planta Med. 2003 Aug;69(8):770-2. PubMed PMID: 14531031.
