MedKoo Cat#: 563395 | Name: EBPC
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

EBPC is a potent aldose reductase inhibitor.

Chemical Structure

EBPC
EBPC
CAS#4450-98-0

Theoretical Analysis

MedKoo Cat#: 563395

Name: EBPC

CAS#: 4450-98-0

Chemical Formula: C14H15NO4

Exact Mass: 261.1001

Molecular Weight: 261.27

Elemental Analysis: C, 64.36; H, 5.79; N, 5.36; O, 24.49

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 550.00 2 Weeks
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Related CAS #
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Synonym
EBPC; 1-EBPC; NSC 229530; NSC229530; NSC-229530
IUPAC/Chemical Name
Ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
InChi Key
IGYRPDIWSYGHMY-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H15NO4/c1-2-19-14(18)11-9-15(13(17)12(11)16)8-10-6-4-3-5-7-10/h3-7,16H,2,8-9H2,1H3
SMILES Code
O=C(C1=C(O)C(N(CC2=CC=CC=C2)C1)=O)OCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 261.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 29029610; PubMed Central PMCID: PMC5640944. 7: Huang J, Zhang Z, Yang Y, Wang R, Zhao J, Jian F, Ning C, Zhang L. New Genotypes of Enterocytozoon bieneusi Isolated from Sika Deer and Red Deer in China. Front Microbiol. 2017 May 18;8:879. doi: 10.3389/fmicb.2017.00879. eCollection 2017. PubMed PMID: 28572794; PubMed Central PMCID: PMC5435827. 8: Li W, Deng L, Wu K, Huang X, Song Y, Su H, Hu Y, Fu H, Zhong Z, Peng G. Presence of zoonotic Cryptosporidium scrofarum, Giardia duodenalis assemblage A and Enterocytozoon bieneusi genotypes in captive Eurasian wild boars (Sus scrofa) in China: potential for zoonotic transmission. Parasit Vectors. 2017 Jan 6;10(1):10. doi: 10.1186/s13071-016-1942-2. PubMed PMID: 28061911; PubMed Central PMCID: PMC5219718. 9: Prasertbun R, Mori H, Pintong AR, Sanyanusin S, Popruk S, Komalamisra C, Changbunjong T, Buddhirongawatr R, Sukthana Y, Mahittikorn A. Zoonotic potential of Enterocytozoon genotypes in humans and pigs in Thailand. Vet Parasitol. 2017 Jan 15;233:73-79. doi: 10.1016/j.vetpar.2016.12.002. Epub 2016 Dec 5. PubMed PMID: 28043391. 10: Qi M, Jing B, Jian F, Wang R, Zhang S, Wang H, Ning C, Zhang L. Dominance of Enterocytozoon bieneusi genotype J in dairy calves in Xinjiang, Northwest China. Parasitol Int. 2017 Feb;66(1):960-963. doi: 10.1016/j.parint.2016.10.019. Epub 2016 Oct 26. PubMed PMID: 27794506. 11: Deng L, Li W, Yu X, Gong C, Liu X, Zhong Z, Xie N, Lei S, Yu J, Fu H, Chen H, Xu H, Hu Y, Peng G. First Report of the Human-Pathogenic Enterocytozoon bieneusi from Red-Bellied Tree Squirrels (Callosciurus erythraeus) in Sichuan, China. PLoS One. 2016 Sep 28;11(9):e0163605. doi: 10.1371/journal.pone.0163605. eCollection 2016. Erratum in: PLoS One. 2016 Dec 19;11(12 ):e0168631. PubMed PMID: 27683278; PubMed Central PMCID: PMC5040432. 12: Zhang XX, Cong W, Liu GH, Ni XT, Ma JG, Zheng WB, Zhao Q, Zhu XQ. Prevalence and genotypes of Enterocytozoon bieneusi in sika deer in Jilin province, Northeastern China. Acta Parasitol. 2016 Mar;61(2):382-8. doi: 10.1515/ap-2016-0050. PubMed PMID: 27078663. 13: Qi M, Wang R, Wang H, Jian F, Li J, Zhao J, Dong H, Zhu H, Ning C, Zhang L. Enterocytozoon bieneusi Genotypes in Grazing Horses in China and their Zoonotic Transmission Potential. J Eukaryot Microbiol. 2016 Sep;63(5):591-7. doi: 10.1111/jeu.12308. Epub 2016 Mar 8. PubMed PMID: 26909747. 14: Shi K, Li M, Wang X, Li J, Karim MR, Wang R, Zhang L, Jian F, Ning C. Molecular survey of Enterocytozoon bieneusi in sheep and goats in China. Parasit Vectors. 2016 Jan 19;9:23. doi: 10.1186/s13071-016-1304-0. PubMed PMID: 26782742; PubMed Central PMCID: PMC5024852. 15: Zhao W, Zhang W, Yang Z, Liu A, Zhang L, Yang F, Wang R, Ling H. Genotyping of Enterocytozoon bieneusi in Farmed Blue Foxes (Alopex lagopus) and Raccoon Dogs (Nyctereutes procyonoides) in China. PLoS One. 2015 Nov 6;10(11):e0142611. doi: 10.1371/journal.pone.0142611. eCollection 2015. Erratum in: PLoS One. 2015;10(11):e0143992. PubMed PMID: 26544711; PubMed Central PMCID: PMC4636423. 16: Wan Q, Lin Y, Mao Y, Yang Y, Li Q, Zhang S, Jiang Y, Tao W, Li W. High Prevalence and Widespread Distribution of Zoonotic Enterocytozoon bieneusi Genotypes in Swine in Northeast China: Implications for Public Health. J Eukaryot Microbiol. 2016 Mar-Apr;63(2):162-70. doi: 10.1111/jeu.12264. Epub 2015 Sep 23. PubMed PMID: 26333563. 17: Tian GR, Zhao GH, Du SZ, Hu XF, Wang HB, Zhang LX, Yu SK. First report of Enterocytozoon bieneusi from giant pandas (Ailuropoda melanoleuca) and red pandas (Ailurus fulgens) in China. Infect Genet Evol. 2015 Aug;34:32-5. doi: 10.1016/j.meegid.2015.06.015. Epub 2015 Jun 12. PubMed PMID: 26079276. 18: Zhang Z, Huang J, Karim MR, Zhao J, Dong H, Ai W, Li F, Zhang L, Wang R. Zoonotic Enterocytozoon bieneusi genotypes in Pere David's deer (Elaphurus davidianus) in Henan, China. Exp Parasitol. 2015 Aug;155:46-8. doi: 10.1016/j.exppara.2015.05.008. Epub 2015 May 14. PubMed PMID: 25982030. 19: Zhao W, Zhang W, Yang D, Zhang L, Wang R, Liu A. Prevalence of Enterocytozoon bieneusi and genetic diversity of ITS genotypes in sheep and goats in China. Infect Genet Evol. 2015 Jun;32:265-70. doi: 10.1016/j.meegid.2015.03.026. Epub 2015 Mar 27. PubMed PMID: 25818401. 20: Jiang Y, Tao W, Wan Q, Li Q, Yang Y, Lin Y, Zhang S, Li W. Zoonotic and Potentially Host-Adapted Enterocytozoon bieneusi Genotypes in Sheep and Cattle in Northeast China and an Increasing Concern about the Zoonotic Importance of Previously Considered Ruminant-Adapted Genotypes. Appl Environ Microbiol. 2015 May 15;81(10):3326-35. doi: 10.1128/AEM.00328-15. Epub 2015 Mar 6. Erratum in: Appl Environ Microbiol. 2015 Aug;81(15):5278. PubMed PMID: 25746997; PubMed Central PMCID: PMC4407225.